Effect of Apolipoprotein E epsilon 4 on the association between health behaviors and cognitive function in late midlife [PDF]
, 2010 The extent to which the effect of risk factors on cognitive ageing is dependent on APOE epsilon 4 remains unclear. The objective of this study is to examine whether APOE epsilon 4 allele modifies the association between health behaviors and cognition in ...
Kumari, Meena +19 more
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Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer [PDF]
, 2023 Apolipoprotein E (apoE) has previously been reported to play vital roles in tumor progression. However, the impact of apoE on colorectal cancer (CRC) metastasis remains largely unexplored.
Mengchen Shi +15 more
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Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
, 2006 Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
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Investigation of APOE isoforms and the association between APOE E3 and E4 with migraine in the Australian Caucasian population [PDF]
, 2013 Migraine is a debilitating neurovascular disease that is associated with pulsating head pain accompanied by nausea, vomiting, photophobia, phonophobia and sometimes visual sensory disturbances.
Stuart, Shani +8 more
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APOE4 Status and cognitive function in middle-aged and elderly people
Balkan Journal of Medical Genetics, 2023 APOE is one of the prominent genes involved in the increased risk of developing Alzheimer’s disease, but its effect on cognition in patients who are not yet diagnosed with dementia or mild cognitive impairment is relatively understudied.
Pavel N.A. +4 more
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Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice [PDF]
, 2005 Plasma apolipoprotein E (apoE) is a 34-kDa polymorphic protein which has atheroprotective actions by clearing remnant lipoproteins and sequestering excess cellular cholesterol.
Dickson, G +7 more
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Терапевтический архив, 2015 During phylogenesis, all fatty acids (FA) were initially transported to cells by apoА-I high-density lipoproteins (HDL) in polar lipids. Later, active cellular uptake of saturated, monoenoic and unsaturated FA occurred via triglycerides (TG) in low ...
V N Titov, T A Rozhkova, A V Aripovsky
doaj
APOE polymorphism and its effect on plasma C-reactive protein levels in a large general population sample [PDF]
, 2010 The literature on association between apolipoprotein E (APOE) gene variations and plasma levels of C-reactive protein (CRP) remains inconsistent, mainly due to low statistical power of previous studies.
Pikhart, H. +6 more
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Genetic aspects of digestive diseases. Part 1
Терапевтический архив, 2010 The paper presents the data available in the literature on mutations in known genes in pancreatitis, such as cationic trypsinogen (PRSS1), pancreatic secretory trypsin inhibitor (PSTI/SPINK1), cystic fibrosis (CFTR), and apolipoprotein E (APOE) genes, as
Irina Nikolaevna Grigor'eva +15 more
doaj
Epigenetic considerations of the APOE gene
Biomolecular Concepts, 2015 The apolipoprotein E (APOE) gene is robustly linked with numerous physiological conditions, including healthy aging, altered cardiovascular fitness, and cognitive function.
Yu Chang-En, Foraker Jessica
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