Results 151 to 160 of about 132,750 (308)
ApoE reguliert das Überleben kortikospinaler Neurone durch ApoER2
, 2013 This study was designed to characterize the role of ApoER2 and its ligand ApoE in the regulation of neuronal survival of normally aging CSN and after axonal injury.
Farsian, Farnas
core
Advanced Intelligent Discovery, EarlyView.scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta +3 more
wiley +1 more source
, 2011 Both domestically and internationally, retaining social workers in statutory child protection and welfare work has been identified as a problem. However, this issue appears to receive only modest attention from researchers. This paper reports on the findings of a study that examined the retention of ‘front line’ child protection and welfare social ...
openaire +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley +1 more source
This paper is concerned with those individuals who do not fit easily or comfortably into traditional notions of employment. Variously described as 'self-employed', 'sole traders', 'own account workers,' 'freelancers,' 'independent contractors' - or more accurately, as independent professionals (IPros ...
openaire +1 more source
Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert +31 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou +4 more
wiley +1 more source
Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community
Annals of Neurology, EarlyView.Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta +11 more
wiley +1 more source
Synthesis of the WXYZA'B'C'D'E'F' Ring of Maitotoxin
Journal of Synthetic Organic Chemistry, Japan, 2023 Umeno, Keitaro, Oishi, Tohru
openaire +1 more source