Results 241 to 250 of about 132,750 (308)
Inactivation of interleukin-15 reduces spontaneous atherosclerosis in <i>apolipoprotein E</i>-deficient mice. [PDF]
Dadoo O +10 more
europepmc +1 more source
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina +7 more
wiley +1 more source
Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk. [PDF]
Peña-Tauber A +24 more
europepmc +1 more source
This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata +4 more
wiley +1 more source
Mendelian randomization evidence refines retinal alterations in Alzheimer's disease. [PDF]
Man S, Gao Y, Mou K, Gao Y, Zhang M.
europepmc +1 more source
Demographic and Clinical Characteristics of Patients Treated With Lecanemab Stratified by Amyloid-Related Imaging Abnormality Status. [PDF]
Rohatgi S +6 more
europepmc +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
The dual role of APOE ε4 allele in cerebral small vessel disease: independent genetic effects and effect modification of traditional risk factors. [PDF]
Liu F, Gou Y.
europepmc +1 more source

