Utilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older [PDF]
, 2004 Apolipoprotein E (APOE), vitamin B12, and folate were examined in relation to free recall among 167 community-based older adults. Cognitive support at encoding and retrieval was also taken into account.
Kivipelto, M, Wahlin, A, Bunce, D
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The associations of PON1 and APOE polymorphisms with plasma lipid levels and the risk for late complications in type 2 diabetes patients [PDF]
Journal of Medical Biochemistry, 2023 Background: Besides good glycemic control, also control of lipid levels can effectively prevent or delay late type 2 diabetes (T2D) complications. As apolipoprotein E (APOE) and paraoxonase 1 (PON1) were shown to suppress atherosclerosis, we investigated
Klen Jasna, Goričar Katja, Dolžan Vita
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Familial dysbetalipoproteinemia: highly atherogenic and underdiagnosed disorder
Кардиоваскулярная терапия и профилактика, 2021 Familial dysbetalipoproteinemia (FD) is a genetic, highly atherogenic disorder. The penetrance of FD depends on the patient’s lifestyle and concomitant diseases. Despite the fact that FD was described almost half a century ago, it is still insufficiently
A. V. Blokhina +3 more
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Journal of Integrative Neuroscience, 2022 Background: Cognitive interventions (CIs) in the elderly are activities that seek to improve cognitive performance and delay its deterioration. Our objectives were to study potential genetic predictors of how a CI program may influence immediate and ...
Pedro Montejo Carrasco +4 more
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The Suggestive Effect of Apo A, Apo B, and Apo A/Apo B on Erectile Dysfunction [PDF]
The Journal of Sexual Medicine, 2021 ABSTRACTBackgroundErectile dysfunction (ED) is closely related to coronary heart disease (CHD). Apolipoprotein (Apo) A1, Apo B, and Apo A/Apo B are known to be predictive factors for CHD. They are not yet a definite laboratory marker for the diagnosis of ED in cardiology. Therefore, we investigated the association between Apo A1, Apo B, and Apo A/Apo B,
Xiucheng, Li, Dongjie, Li
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APOE4 dysregulates autophagy in cultured cells
Autophagy Reports, 2022 Human APOE4 (apolipoprotein E4 isoform) is a powerful genetic risk factor for late-onset Alzheimer disease (AD). Many groups have investigated the effect of APOE4 on the degradation of amyloid β (Aβ), the main component of plaques found in the brains of ...
Gianna M. Fote, Joan S. Steffan
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Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Intracerebral hemorrhage (ICH) occurs mostly in the striatum. In ICH, blood prolactin level increases 3-fold. The effects of intracerebroventricular injection (ICV) of prolactin on motor disorders will be investigated. Materials and Methods:
Shiba Yousefvand +6 more
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Research Results in Pharmacology, 2023 Introduction: The aim of this study was to evaluate the processes of bone remodeling and osteoreparation in modeling femoral fracture in mice with zero expression of 11β-HSD2 (11β-HSD2-/-) or both 11β-HSD2 and apolipoprotein e (11β-HSD2-/-/ApoE ...
Mikhail V. Korokin +12 more
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ApoE and ApoE Nascent-Like HDL Particles at Model Cellular Membranes: Effect of Protein Isoform and Membrane Composition. [PDF]
, 2021 Apolipoprotein E (ApoE), an important mediator of lipid transportation in plasma and the nervous system, plays a large role in diseases such as atherosclerosis and Alzheimer's.
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Molecular recognition of the interaction between ApoE and the TREM2 protein
Translational Neuroscience, 2022 Alzheimer’s disease (AD) is the most common type of dementia. The ε4 allele of the apolipoprotein E (ApoE) gene is the strongest known genetic risk factor for late-onset AD.
Mai Zhenhua +5 more
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