Results 31 to 40 of about 135,666 (308)

APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age [PDF]

, 2012
Copyright © 2012 IOS PressThis article has been made available through the Brunel Open Access Publishing Fund.The apolipoprotein E (APOE) ε4 allele is a risk factor for the neuropathological decline accompanying Alzheimer's disease (AD) while, conversely,
Bunce, David, Perminder Sachdev, Cherbuin, N, Anstey, KJ, David Bunce, Kaarin J. Anstey, Bunce, D, Prapti Gautam, Simon Easteal, Gautam, P, Easteal, S, Cherbuin, Nicolas, Anstey, Kaarin, Gautam, Prapti, Sachdev, Perminder Singh, Nicolas Cherbuin, Sachdev, P, Easteal, Simon   +17 more
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Association Analysis of Polymorphisms in BIN1, MC1R, STARD6 and PVRL2 with Mild Cognitive Impairment in Elderly Carrying APOE ϵ4 Allele

Neuropsychiatric Disease and Treatment, 2021
Yue Wu,1,* Jiajun Yin,2,* Bixiu Yang,3 Li Tang,4 Wei Feng,5 Xiaowei Liu,1 Xingfu Zhao,1 Zaohuo Cheng1 1Department of Geriatric Psychiatry, The Affiliated Wuxi Mental Health Center with Nanjing Medical University, Wuxi, Jiangsu Province, People’s ...
Wu Y, Yin J, Yang B, Tang L, Feng W, Liu X, Zhao X, Cheng Z   +7 more
doaj  

Giresun İlinde FV, FXIII, ACE, ApoE Gen Varyantlarının Prevelansı ve Koroner Arter Hastalığı Profiline Etkilerinin Araştırılması

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2019
Amaç: Ateroskleroz kaynaklı Koroner Arter Hastalığı (KAH), multifaktöriyel ve poligenik kompleks bir hastalıktır. Son yıllarda yapılan çalışmalarda KAH ile ilişkili bazı genetik varyantlar öne çıkmıştır.
Erhan Teker, Aynur Dağlar Aday, Hülya Yılmaz Aydoğan, Ayşegül Başak Akadam-teker   +3 more
doaj   +1 more source

APOE genetic variants and apoE, miR-107 and miR-650 levels in Alzheimer’s disease

Folia Neuropathologica, 2019
Alzheimer’s disease (AD) is a progressive neurodegenerative dementia in adults. Pathogenesis of AD depends on various factors, including APOE genetic variants, apolipoprotein E (apoE) phenotype and oxidative stress, which may promote both DNA and RNA ...
Michal Prendecki, Jolanta Florczak-Wyspianska, Marta Kowalska, Jan Ilkowski, Teresa Grzelak, Katarzyna Bialas, Wojciech Kozubski, Jolanta Dorszewska   +7 more
doaj   +1 more source

ApoE-expressing astrocytes physically interact with injury-induced GFP-expressing dendrites.

, 2020
(A) Representative section of the contralateral and ipsilateral cortex and hippocampus 4 weeks after Controlled Cortical Impact and stereotaxic injection of GFP-expressing retroviruses in the dentate gyrus of a wildtype mouse reveals the typical ...
Tzong-Shiue Yu (695757), Yacine Tensaouti (8520171), Steven G. Kernie (8520174)   +2 more
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ApoE-modified liposomes encapsulating resveratrol and salidroside alleviate manifestations of Alzheimer’s disease in APP/PS-1 mice

, 2023
Alzheimer’s disease (AD) is a neurodegenerative disease that is associated with aging and is influenced by both genetic and environmental factors. Several studies and clinical trials have demonstrated that resveratrol (Res) and salidroside (Sal) are not ...
Xiu-Ying Li (16911670), Liang Kong (154890), Yang Yu (4292), Mu-Han Chen (16911661), Juan Zang (16911667), Xue-Tao Li (4806609), Xin-Ze Liu (12644240), Lu Zhang (50563), Yang Liu (4829), Xiu-Wu Qu (16911664), Rui-Bo Guo (12644237)   +10 more
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Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders

Disease Models & Mechanisms, 2020
The importance of apolipoprotein E (APOE) in late-onset Alzheimer's disease (LOAD) has been firmly established, but the mechanisms through which it exerts its pathogenic effects remain elusive.
Julia Gamache, Young Yun, Ornit Chiba-Falek   +2 more
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APOE-independent dEQ biomarkers (unrelated to APOE by Path c).

, 2017
APOE-independent dEQ biomarkers (unrelated to APOE by Path c).
Ram Bishnoi (3836311), Donald R. Royall (695528), Safa Al-Rubaye (3836308), Raymond F. Palmer (695527)   +3 more
core   +1 more source

Ferroptosis-Related APOE, BCL3 and ALOX5AP Gene Polymorphisms are Associated with the Risk of Thyroid Cancer

Pharmacogenomics and Personalized Medicine, 2022
Zhifu Xiao,1,* Haixia Zhao2,* 1Department of Thyroid Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China; 2Central Lab, General Hospital of Taiyuan Iron and Steel Group, Taiyuan, Shanxi, 030003 ...
Xiao Z, Zhao H
doaj  

ApoE gene therapy to treat hyperlipidemia and atherosclerosis [PDF]

, 2006
Atherosclerosis is the leading cause of death in industrialized countries and is becoming an increasingly worldwide risk to health. Apolipoprotein E (ApoE) is a blood circulating protein with pleiotropic atheroprotective properties that has emerged as a ...
Owen, JS, Evans, V, Harris, JD, Evans, Vanessa C   +3 more
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