Results 121 to 130 of about 121,312 (312)
, 2012 Background: The blood-brain barrier (BBB) represents an insurmountable obstacle for most drugs thus obstructing an effective treatment of many brain diseases.
Tikva Vogel +29 more
core +1 more source
Annals of Neurology, EarlyView.Objective Both high and declining blood pressure (BP) are associated with risk of cognitive decline in older adults, and women have higher rates of hypertension and faster cognitive decline in late‐life. In old age, the relationship between changes in BP and changes in cognition is complex, and although sex differences in cognitive function and decline
Nicholas W. Baumgartner +4 more
wiley +1 more source
Lesional macrophage-derived apoE.
, 2013 Immunofluorescent images of Apoeh/hLysM-Cre (A,C) and Apoeh/h mice (B,D; scale bar = 250 µm) aortic roots; anti-Mac-2 (green), and apoE (red). Quantification of lesion area (E), macrophage positive and % of area (F–G); n = 7.
Nathalie Gaudreault (221057) +5 more
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Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
MOLECULAR-GENETICAL MARKERS OF LIPID ABNORMALITIES AND SUDDEN CARDIAC DEATH
Атеросклероз, 2017 Sudden cardiac death is one of main problem of modern medicine. Sudden cardiac death is about 50 % of all cardiac deaths. The main part of people who died of sudden cardiac death didn’t have any cardiac illnesses.
A. A. Ivanova
doaj
Verbal memory improvement in first-episode psychosis APOE-ε4 carriers: a pleiotropic effect?
, 2017 Fidel Vila-Rodriguez,1 Donna J Lang,2 Heather Baitz,3 Kristina Gicas,3 Allen E Thorton,3 Thomas S Ehmann,1 Geoff N Smith,1 Alasdair M Barr,4 Ivan J Torres,1 Lili C Kopala,1 G William MacEwan,1 Daniel J Müller,5 James L Kennedy,5 William G ...
Kopala LC +13 more
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Some common candidate genes in arterial hypertension and gallstlone disease pathogenesis
Атеросклероз, 2014 Gallstone disease (GSD) and arterial hypertension (AH) have many common risk factors – age, overweight, dyslipidemia, low physical activity, diabetes mellitus, in addition, the presence of AH is considered by many authors as a risk factor for GSD ...
M. S. Lebedeva +3 more
doaj
Corpus-based analysis on the use of 'this' and 'it'
, 2018 Käesoleva bakalaurusetöö “Korpuseanalüüs asesõnade this ja it kasutamisest” teemaks on inglise keelt õppivate eestlaste asesõnade this ja it kasutamist. Analüüsiks oli võetud 2014. aasta Tartu Ülikooli õppijakeele korpus, mis koosnes 127-st tekstist, mis olid inglise keele ja kirjanduse õppe sisseastumiseksami kolmanda küsimuse vastused. Töö eesmärgiks
openaire +1 more source
APOE as a risk factor for Alzheimer’s disease and lipid metabolism disorders: molecular analysis
The gene encoding apolipoprotein E (APOE) plays a key role in many biological processes, including lipid metabolism, brain homeostasis, and functioning of the circulatory system.
Szafraniec, Kacper +7 more
core +1 more source
ApoE reguliert das Überleben kortikospinaler Neurone durch ApoER2
, 2013 This study was designed to characterize the role of ApoER2 and its ligand ApoE in the regulation of neuronal survival of normally aging CSN and after axonal injury.
Farsian, Farnas
core