Results 211 to 220 of about 135,666 (308)

Protosappanin A Alleviates Atherosclerosis by Regulating the MDM2/GPX4 Axis‐Mediated Endothelial Ferroptosis

Phytotherapy Research, EarlyView.
PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu, Lin Zhu, Wenwei Yang, Mengnan Li, Zhixin Wu, Shude Sun, Yabin Zhou   +6 more
wiley   +1 more source

'SU' AND 'SUBASHIRA' OF ROOFED MUD-WALL

Journal of Architecture and Planning (Transactions of AIJ), 2006
HAYAMI, Yohei, SHINKAWA, Tatsuhiro, TSUCHIMOTO, Toshikazu   +2 more
openaire   +1 more source

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

Numeracy and recall of Alzheimer's disease risk information: Effects of risk format in a Latino community. [PDF]

Patient Educ Couns
Rodriguez S, Wetmore JB, Diaz Caro D, Cabán M, Uhlmann WR, Roberts JS, Siegel K, Ottman R.   +7 more
europepmc   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

<i>ECH1</i>-Deficiency-Mediated Polyunsaturated Fatty Acid Accumulation Promotes Vascular Smooth Muscle Cell Ferroptosis and Chronic-Kidney-Disease-Associated Plaque Vulnerability. [PDF]

Research (Wash D C)
Bi X, Zhou J, Liu L, Chen Z, Liang B, Tian S, Xiong J, Lan Q, Lv L, Li Y, Xiao T, He T, Zhang J, Nie L, Zhao J.   +14 more
europepmc   +1 more source

A Clinical Study on ''Sudden Cardiac Death''

Juntendo Medical Journal, 1986
openaire   +1 more source

pKa engineering of a near‐infrared fluorescent probe for sensitive imaging of oxidative stress in atherosclerotic plaques

Smart Molecules, EarlyView.
A pKa‐engineered near‐infrared fluorescent probe (DCM‐2F‐B) enables sensitive imaging of oxidative stress in atherosclerotic plaques. Difluoro substitution lowers the phenolic hydroxyl pKa from 9.1 to 6.0, achieving near‐complete ionization at physiological pH.
Qianqian Yu, Jiahui Liang, Tijian Zhou, Qiaomeng Chen, Xuechun Yan, Zhikang Zheng, Huyou Wang, Jihong Liu, Yi Dong, Wei‐Hong Zhu, Qi Wang   +10 more
wiley   +1 more source