Results 231 to 240 of about 135,666 (308)

Alcohol consumption and cognitive function: A systematic review and dose–response meta‐analysis of 20 cohort studies

Addiction, EarlyView.
Abstract Background and aims Amid ongoing debate on whether low‐to‐moderate alcohol consumption reduces cardiovascular risk, studies examining the association between alcohol consumption and cognitive function have reported inconsistent results. To quantitatively assess this association, we conducted a dose–response meta‐analysis of cohort studies ...
Sooyeun Choi, Youjin Je
wiley   +1 more source

APOE in subjective cognitive decline: a systematic review and meta-analysis. [PDF]

J Neurol
Alonge P, Baiamonte L, Gerardi G, Torrente A, Lo Mauro E, Veronese N, Labate A, Monastero R.   +7 more
europepmc   +1 more source

Evidence for Reduced Somatic T‐Cell Receptor Sequence Diversity Profiles Among Midwestern Amish in an Aging Cohort Study

Annals of Human Genetics, EarlyView.
ABSTRACT Background The causes of late onset Alzheimer disease (LOAD) are not known but several recent lines of evidence implicate the adaptive immune system. Objective To characterize the adaptive immune system among Midwestern Amish participating in longitudinal studies of aging.
Lauren A. Cruz, Shiying Liu, Kristy L. Miskimen, Jessica N. Cooke Bailey, Tyler Kinzy, Yeunjoo E. Song, Renee A. Laux, Penelope Miron, Paula K. Ogrocki, Alan J. Lerner, Audrey Lynn, Sarada L. Fuzzell, Sherri D. Hochstetler, Ioanna Konidari, Jacob L. McCauley, William K. Scott, Margaret A. Pericak‐Vance, Jonathan L. Haines, Dana C. Crawford   +18 more
wiley   +1 more source

Fibronectin mediates APOE4-driven blood-brain barrier dysfunction in Alzheimer's disease. [PDF]

Nat Aging
Bhattarai P, Yilmaz E, Cakir EÖ, Tayran H, Haq I, Murphy D, Keller JN, Le Grand Q, Eschbach JO, Celikkaya H, Cosacak MI, Yüceer Korkmaz H, Lee AJ, Haage V, Ma Y, Wang X, Nelson N, Lin W, Zhang Y, Turgutalp B, de Leeuw SM, Patel R, Jülich D, İş Ö, Holley SA, De Jager PL, Freudenberg U, Werner C, St George-Hyslop P, Ertekin-Taner N, Debette S, Elahi FM, Fisher ES, Phatnani H, Teich AF, Tubbesing K, Bertucci T, Temple S, Nuriel T, Vardarajan BN, Mayeux R, Kizil C.   +41 more
europepmc   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

NSG Mice Lacking Apoe: An Immunodeficient Mouse Model of Atherosclerosis. [PDF]

FASEB J
Megathlin HR, Burzenski L, Coleman DA, Albert B, Farley ML, Brehm MA, Greiner DL, Shultz LD.   +7 more
europepmc   +1 more source

Clinicopathological and molecular heterogeneity of amyloid‐β in unnatural deaths under 70 years: A forensic autopsy–based study

Brain Pathology, EarlyView.
This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata, Yukiko Hata, Koji Yoshida, Ryo Tanaka, Shigeo Murayama   +4 more
wiley   +1 more source

USF2-Mediated APOE-Cholesterol Signaling Promotes CTC Clustering and Metastasis in Non-Small Cell Lung Cancer. [PDF]

Int J Mol Sci
Li Z, Cui M, Sun L, Qin H, Shen X, Gao W.   +5 more
europepmc   +1 more source

The 'State' of 'public' broadcasting in Greece

, 2010
openaire   +1 more source