Results 131 to 140 of about 121,312 (312)

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

open access: yesArthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald   +9 more
wiley   +1 more source

''Wist U ervan?''

open access: yes, 2007
De vuurwerkramp in Enschede, de ingestorte grachttrap in Utrecht, de moord op Theo van Gogh, de aanslagen van 11 september, de Bijlmerramp, de verspreiding van de SARS-pandemie, de Bijlmerramp ... Welke ramp er ook geschiedt, welke fouten er ook worden gemaakt, steevast wordt de vraag gesteld: waren de betrokken autoriteiten op de hoogte en zo ja, had ...
openaire   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

open access: yesBMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai   +14 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

The role of inflammation, oxidative stress and the apolipoprotein E genotype in HIV-associated cognitive impairment: a clinical, biochemical and neuro-imaging study

open access: yes, 2010
Includes abstract.Includes bibliographical references (leaves 113-135).Twenty percent of HIV-infected patients develop HIV-associated neurocognitive disorders (HAND), a spectrum of neurological diseases which includes HIV-associated dementia (HAD), a ...
Mahne, Anna Cecilia
core  

Ox-ApoE binds weakly to emulsion particles.

open access: yes, 2013
A. Ox-ApoE binding with triglyceride-PC emulsion particles. Native and ox-ApoE were incubated with triglyceride-PC emulsion particles at room temperature for 1 hr with gentle shaking.
Youfeng Yang (382219)   +4 more
core   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi   +6 more
wiley   +1 more source

Synthesis of the WXYZA'B'C'D'E'F' Ring of Maitotoxin

open access: yesJournal of Synthetic Organic Chemistry, Japan, 2023
Umeno, Keitaro, Oishi, Tohru
openaire   +1 more source

Transitioning towards sustainability: The 'what', 'why' and 'how' of the integration of sustainable practices into business models

open access: yes, 2022
[ES] En el ecosistema empresarial actual, la sostenibilidad se está convirtiendo cada vez más en un elemento vital para la prosperidad a largo plazo de las empresas. La sostenibilidad está ganando importancia paulatinamente, y actualmente se está convirtiendo en una tendencia imparable en todas las dimensiones de nuestro marco socioeconómico.
Díez-Martínez, Inés   +1 more
openaire   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

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