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Testing novel apolipoprotein A-I mimetic peptides as a treatment of atherosclerosis
2017Atherosclerosis is an inflammatory disease that stems from the accumulation of cholesterol in the artery wall. In the initial stages of atherosclerosis, low density lipoproteins (LDL) from the plasma enter and accumulate within the arterial wall and become modified via oxidation.
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[Effect of apolipoprotein A-I mimetic peptides on cholesterol efflux in RAW264.7 cells].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2012To determine the effect and possible mechanism of an apolipoprotein (apo) A-I mimetic peptide, D-4F, on cholesterol efflux in RAW264.7 macrophages.RAW264.7 macrophages were incubated in the medium containing 8-bromo cAMP (8-Br-cAMP, 0.5 mmol/L) and ox-LDL (50 μg/mL) for 24 h.
Qiong, Xie, Shuiping, Zhao
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Apolipoprotein-mimetic Peptides: Current and Future Prospectives
Current Protein and Peptide Science, 2022Abhay H Pande +2 more
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The A's Have It: Developing Apolipoprotein A-I Mimetic Peptides Into a Novel Treatment for Asthma.
Chest, 2017New treatments are needed for patients with asthma who are refractory to standard therapies, such as individuals with a phenotype of "type 2-low" inflammation. This important clinical problem could potentially be addressed by the development of apolipoprotein A-I (apoA-I) mimetic peptides.
Xianglan, Yao +4 more
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Abstract: P1154 IN VITRO PROPERTIES OF AN APOLIPOPROTEIN A-I MIMETIC PEPTIDE
Atherosclerosis Supplements, 2009B di Bartolo +5 more
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Structure/Function Relationships of Apolipoprotein A-I Mimetic Peptides
Circulation Research, 2010Alan Remaley +2 more
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Apolipoprotein A-I Mimetic Peptides for the Treatment of Coronary Artery Disease
Current Cardiology Reviews, 2005openaire +1 more source