Results 181 to 190 of about 92,484 (303)

The High- and low-activity forms of human plasma phospholipid transfer protein (PLTP)

open access: yes, 2006
ei tietoa saavutettavuudesta unknown ...
Jänis, Minna T, Jänis, Minna
core  

Depletion of microglial compensation in glial network: Disease‐associated response dynamics in the revised amyloid hypothesis

open access: yesNeuroprotection, EarlyView.
The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei   +3 more
wiley   +1 more source

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

open access: yesNeuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong   +3 more
wiley   +1 more source

Weight Change Between Pregnancies and Mortality Over 50 Years of Follow‐Up

open access: yesObesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the link between postpartum weight retention (PPWR) and long‐term mortality. Methods In this secondary analysis of 8165 women with ≥ 2 pregnancies in the Collaborative Perinatal Project (CPP), U.S., 1959–1966, with vital status follow‐up through 2016, we used interconception weight change (ICWC) and ...
Yajnaseni Chakraborti   +10 more
wiley   +1 more source

Time‐Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity: The TREAD Randomized Control Trial

open access: yesObesity, EarlyView.
ABSTRACT Objective Examine time‐restricted eating (TRE) as a strategy to promote weight loss and cardiometabolic health in adults with obesity. Methods TRE in obesity and ADipose Tissue (TREAD) was a single‐center 12‐week RCT, involving 1:1 randomization to 10‐h TRE versus standard of care (SOC) in adults with obesity (BMI 30–50 kg/m2) without diabetes
Michael J. Wilkinson   +15 more
wiley   +1 more source

Interaction between Testosterone and Apolipoprotein E ε4 Status on Cognition in Healthy Older Men

open access: yes, 2005
Reduced testosterone levels have been implicated as a potential causative factor in cognitive decline with older age. Men who possess the apolipoprotein E (APOE) 4 allele have an increased risk of developing Alzheimer’s disease; however, no studies have
Chubb, S.A.P.   +6 more
core  

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà   +10 more
wiley   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

open access: yesPhytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi   +15 more
wiley   +1 more source

Apolipoprotein C-II Mimetic Peptide Promotes the Plasma Clearance of Triglyceride-Rich Lipid Emulsion and the Incorporation of Fatty Acids into Peripheral Tissues of Mice. [PDF]

open access: yesJ Nutr Metab, 2019
Komatsu T   +10 more
europepmc   +1 more source

A Study of Apolipoprotein C II

open access: yesThe Journal of Japan Atherosclerosis Society, 1982
Michihiko HAYAKAWA   +7 more
openaire   +2 more sources

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