Results 201 to 210 of about 92,484 (303)

Metabolism of apolipoprotein A-II containing triglyceride rich ApoB lipoproteins in humans. [PDF]

Atherosclerosis, 2015
Desai NK, Ooi EM, Mitchell PD, Furtado J, Sacks FM.   +4 more
europepmc   +1 more source

Comparative Effects of Emerging Lp(a)‐Lowering Agents and PCSK9‐Directed Therapies on Lipoprotein(a): A Network Meta‐Analysis of Randomised Clinical Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Elevated lipoprotein(a) [Lp(a)] is a genetic ASCVD risk factor that often persists despite intensive LDL‐C lowering. We compared the efficacy and safety of emerging Lp(a)‐targeted therapies (siRNAs, antisense oligonucleotides and an oral assembly inhibitor) with PCSK9‐directed therapies.
Jihad Abu Zayed, Nada A. Al‐Awamleh, Mahmoud Hamad, Mohammad Ibrahim Mahmoud Hdaib, Hazem Ayesh   +4 more
wiley   +1 more source

Alteration in oral and non‐oral tissues in ligature‐induced periodontitis mice with the Alzheimer's disease risk factor APOE4

European Journal of Oral Sciences, EarlyView.
Abstract The APOE4 gene, particularly the ε4 allele, is linked to susceptibility to Alzheimer's disease, and periodontitis can cause pathological changes in multiple organs, but combined effects of these conditions and the impact of tumor necrosis factor (TNF)‐α regulation on the combined effects remain unclear.
Ae Ri Kim, Yun‐Jung Yoo, Eun‐Jung Bak   +2 more
wiley   +1 more source

An Elevated Serum Apolipoprotein C-III Concentration is Associated with the Risk of Coronary Heart Disease in a Japanese General Population. The Hidaka Cohort Study. [PDF]

J Atheroscler Thromb
Fujioka Y, Tanaka SI, Tsujino T, Ishida T, Hirata KI.   +4 more
europepmc   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

Bionano Interface Optimization for Rational Lateral Flow Assay Development. [PDF]

ACS Nano
Sadler CJ, Miller M, Darmawan KK, Sandler JP, Ng HC, Shamsabadi A, Creamer A, Robinson CV, Yarovsky I, Stevens MM.   +9 more
europepmc   +1 more source

A Pressure-dependent Model for the Regulation of Lipoprotein Lipase by Apolipoprotein C-II. [PDF]

J Biol Chem, 2015
Meyers NL, Larsson M, Olivecrona G, Small DM.   +3 more
europepmc   +1 more source

The Level of Apolipoprotein A-I Is Associated with a Prognosis in Patients with Chronic Heart Failure Especially in HFmrEF and HFpEF: A Retrospective Cohort Study

XueChun He,1,* FaPeng Li,2,* Jian Zhang,1 ZhiYing Wen,1 YanXiao Li,3 WeiTong Gao,1 HongXia Chen,1 YangGuang Yu,1 YingYing Zheng,1 Xiang Xie1 1Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi ...
Li Y, Zheng Y, Wen Z, Zhang J, Xie X, He X, Li F, Gao W, Chen H, Yu Y   +9 more
core  

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure. [PDF]

Sci Rep, 2018
Yang M, Liu Y, Dai J, Li L, Ding X, Xu Z, Mori M, Miyahara H, Sawashita J, Higuchi K.   +9 more
europepmc   +1 more source