Primary structure of apolipoprotein A-II from inbred mouse strain BALB/c.
The primary structure of apolipoprotein A-II (apoA-II) isolated from the plasma high density lipoprotein (HDL) fraction of the inbred mouse strain BALB/c is described in this work. The complete 78 amino acid protein sequence was determined by proteolytic
C G Miller +3 more
doaj +1 more source
The Alzheimer variant of Lewy body disease: A pathologically confirmed case-control study [PDF]
The objective of the study was to identify clinical features that distinguish patients with dementia with Lewy bodies (DLB), who were classified as Alzheimer's disease ( AD) patients, from patients with AD.
Busch, R. +7 more
core +1 more source
Gain and loss events in the evolution of the apolipoprotein family in vertebrata
Background Various apolipoproteins widely distributed among vertebrata play key roles in lipid metabolism and have a direct correlation with human diseases as diagnostic markers.
Jia-Qian Liu +5 more
doaj +1 more source
Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis
High levels of circulating triglycerides (TGs), or hypertriglyceridemia, are key components of metabolic diseases, such as type 2 diabetes, metabolic syndrome, and CVD.
Brynne E. Whitacre +5 more
doaj +1 more source
Homologue of mammalian apolipoprotein A-II in non-mammalian vertebrates [PDF]
Although apolipoprotein with molecular weight 14 kDa (apo-14 kDa) is associated with fish plasma high-density lipoproteins (HDLs), it remains to be determined whether apo-14 kDa is the homologue of mammalian apoA-II. We have obtained the full cDNA sequences that encode Japanese eel and rainbow trout apo-14 kDa.
Malay, Choudhury +4 more
openaire +2 more sources
Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Abt, Markus +18 more
core +2 more sources
Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? [PDF]
Data from basic science experiments is overwhelmingly supportive of the causal role of immune-inflammatory response(s) at the core of atherosclerosis, and therefore the theoretical potential to manipulate the inflammatory response to prevent ...
Abbas +173 more
core +2 more sources
Tissue factor (coagulation factor III) inhibition by apolipoprotein A-II.
Apolipoprotein A-II (apoA-II) has been shown to inhibit tissue factor participation in the activation of coagulation factor X by factor VIIa. The magnitude of inhibition was dependent on the concentration of the enzyme (factor VIIa) and substrate (factor
S. Carson
semanticscholar +1 more source
Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo +2 more
core +2 more sources
Human apolipoprotein A‐II: complete nucleic acid sequence of preproapoA‐II
The complete cDNA nucleic acid sequence of preproapolipoprotein (apo) A‐II, a major protein constituent of high density lipoproteins, has been determined on clones from a human liver ds‐cDNA library. Clones containing ds‐cDNA for apoA‐II were identified in the human liver ds‐cDNA library using synthetic oligonucleotides as probes.
Lackner, Karl J. +2 more
openaire +2 more sources

