Results 71 to 80 of about 803,874 (212)

Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]

, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A, Dickson, G, Graham, IR, Harris, JD, Owen, JS   +4 more
core  

Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. [PDF]

, 2017
Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Apolipoprotein C-II (APOC2) is an obligatory cofactor for lipoprotein lipase (LPL), the major enzyme catalyzing plasma triglyceride hydrolysis.
Gaudet, Daniel, Liu, Chao, Miller, Yury I   +2 more
core   +1 more source

Influence of Peripheral Artery Disease and Statin Therapy on Apolipoprotein Profiles

International Journal of Vascular Medicine, 2013
Apolipoprotein B is a stronger predictor of myocardial infarction than LDL cholesterol, and it is inversely related to physical activity and modifiable with exercise training.
Andrew W. Gardner, Petar Alaupovic, Donald E. Parker, Polly S. Montgomery, Omar L. Esponda, Ana I. Casanegra   +5 more
doaj   +1 more source

ApoA-I deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis[S]

Journal of Lipid Research, 2011
Apolipoprotein A-II (apoA-II) is the second major apolipoprotein following apolipoprotein A-I (apoA-I) in HDL. ApoA-II has multiple physiological functions and can form senile amyloid fibrils (AApoAII) in mice.
Yaoyong Wang (王耀勇), Jinko Sawashita (澤下仁子), Jinze Qian (钱金泽), Beiru Zhang (张蓓茹), Xiaoying Fu (付笑影), Geng Tian (田耕), Lei Chen (陈磊), Masayuki Mori (森 政之), Keiichi Higuchi (樋口京一)   +8 more
doaj   +1 more source

Protein changes as robust signatures of fish chronic stress: a proteomics approach to fish welfare research [PDF]

, 2020
Background Aquaculture is a fast-growing industry and therefore welfare and environmental impact have become of utmost importance. Preventing stress associated to common aquaculture practices and optimizing the fish stress response by ...
Cerqueira, Marco, Farinha, Ana Paula, Kuehn, Annette, Planchon, Sébastien, Raposo de Magalhães, Cláudia, Revets, Dominique, Rodrigues, Pedro, Schrama, Denise   +7 more
core  

Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]

, 2019
Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria, Dolan, Sharron, Graham, Annette, Lightbody, Richard J., Tarlton, Jamie M.R.   +4 more
core   +1 more source

Polyphenol Interactions with Amyloid Fibrils: A Molecular Docking Study

East European Journal of Physics
Polyphenols, a versatile group of naturally occurring compounds with many favorable biological properties currently attract increasing research interest in the context of their ability to inhibit the formation and to destabilize special protein ...
Uliana Malovytsia, Valeriya Trusova, Mette Thomsen, Kateryna Vus, Olga Zhytniakivska, Galyna Gorbenko   +5 more
doaj   +1 more source

Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants [PDF]

, 2016
Background: the apolipoprotein (APOE) e4 locus is a genetic risk factor for dementia. Carriers of the e4 allele may be more vulnerable to conditions that are independent risk factors for cognitive decline, such as cardiometabolic diseases.
Anderson, Jana, Bailey, Mark E.S., Celis, Carlos, Cullen, Breda, Davies, Gail, Deary, Ian J., Evans, Jon, Lyall, Donald M., Mackay, Daniel, McIntosh, Andrew M., Pell, Jill P., Ritchie, Stuart J., Sattar, Naveed, Smith, Daniel J., Ward, Joey   +14 more
core   +1 more source

The Effect of Training Type on Hepatic Gene expressions of Apolipoprotein A‐I, and Apolipoprotein A‐II among Male Wistar Rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2019
Introdaction: Lipid metabolism disorders, especially raised levels of cholesterol and triglycerides increases the risk of atherosclerosis. This study aimed to investigate the effect of training type including submaximal continuous and high-intensity ...
Bahman Hasanvand, Kobra Karami, YAGHOUB MEHRIALVAR   +2 more
doaj  

Changes in the size of reconstituted high density lipoproteins during incubation with cholesteryl ester transfer protein: the role of apolipoproteins.

Journal of Lipid Research, 1992
It has been reported previously that the particle size distribution of discoidal, reconstituted HDL (r-HDL) changes dramatically during incubation in vitro with cholesteryl ester transfer protein (CETP).
KA Rye, KH Garrety, PJ Barter
doaj   +1 more source