Results 81 to 90 of about 803,874 (212)

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. [PDF]

, 1994
Lipoproteins isolated from normal human plasma can bind and neutralize bacterial lipopolysaccharide (LPS) and may represent an important mechanism in host defense against gram-negative septic shock. Recent studies have shown that experimentally elevating
Kane, JP, Kunitake, ST, Lichenstein, H, Wright, SD, Wurfel, MM   +4 more
core   +1 more source

Apolipoprotein A-II content of human plasma high density lipoproteins measured by radioimmunoassay

Journal of Lipid Research, 1977
A double antibody radioimmunoassay for human ApoA-II is reported. ApoA-II isolated from human plasma high density lipoprotein (HDL) by column chromatography migrated as a single band on polyacrylamide disc gel electrophoresis, had the appropriate amino ...
G Schonfeld, J Chen, W F McDonnell, I Jeng   +3 more
doaj   +1 more source

Biosynthesis and secretion of insect lipoprotein: involvement of furin in cleavage of the apoB homolog, apolipophorin-II/I

Journal of Lipid Research, 2005
The biosynthesis of neutral fat-transporting lipoproteins involves the lipidation of their nonexchangeable apolipoprotein. In contrast to its mammalian homolog apolipoprotein B, however, insect apolipophorin-II/I (apoLp-II/I) is cleaved ...
Marcel M.W. Smolenaars, Marcelle A.M. Kasperaitis, Paul E. Richardson, Kees W. Rodenburg, Dick J. Van der Horst   +4 more
doaj   +1 more source

Generation of Gene-Knockout Mongolian Gerbils via CRISPR/Cas9 System

Frontiers in Bioengineering and Biotechnology, 2020
The Mongolian gerbil (Meriones unguiculatus), a well-known “multifunctional” experimental animal, plays a crucial role in the research of hearing, cerebrovascular diseases and Helicobacter pylori infection.
Yan Wang, Peikun Zhao, Zidai Song, Xiaoyan Du, Xueyun Huo, Jing Lu, Xin Liu, Jianyi Lv, Changlong Li, Meng Guo, Zhenwen Chen   +10 more
doaj   +1 more source

Perivascular adipose tissue inflammation in vascular disease [PDF]

, 2017
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core   +1 more source

One-step screening method for the polymorphism of apolipoproteins A-I, A-II, and A-IV

Journal of Lipid Research, 1982
Apolipoprotein A-I exhibits a polymorphism that can be easily investigated in native serum by a simple method involving incubation of serum in the presence of decylsulfate and beta-mercaptoethanol and subsequent isoelectric focusing.
H J Menzel, R G Kladetzky, G Assmann
doaj   +1 more source

Isolation and characterization of the human apolipoprotein A-II gene. Electron microscopic analysis of RNA:DNA hybrids, nucleotide sequence, identification of a polymorphic MspI site, and general structural organization of apolipoprotein genes.

Journal of Biological Chemistry, 1985
Three cloned apolipoprotein A-II genes were isolated from a human genomic cosmid library constructed in our laboratory. An approximately 3-kilobase HindIII insert containing the entire gene was analyzed by RNA:DNA hybridization and electron microscopy ...
Y. Tsao, C. F. Wei, D. Robberson, A. Gotto, L. Chan   +4 more
semanticscholar   +1 more source

Immunonephelometry of apolipoprotein A-II in hyperlipoproteinemic serum.

Clinical Chemistry, 1983
Abstract Immunonephelometry of apolipoprotein A-II (apo A-II) in serum requires that factors responsible for nonspecific increases of light scattering be eliminated. Complete delipidation is not necessary for immunonephelometry of apo A-II; in fact, light scattering of immunocomplexes from delipidated HDL is greater than from isolated ...
C C, Heuck, I, Erbe, K, Frech, P, Lohse, G, Münscher   +4 more
openaire   +2 more sources

Complement activation and protein adsorption by carbon nanotubes [PDF]

, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel, Green, Malcolm L. H., Salvador-Morales, Carolina, Sim, Edith, Sim, Robert B., Sloan, Jeremy   +5 more
core   +2 more sources

Structural studies of Manduca sexta lipid transfer particle with apolipoprotein-specific antibodies

Journal of Lipid Research, 1995
Studies have been conducted to characterize structural and functional properties of Manduca sexta lipid transfer particle (LTP). LTP is a high molecular weight complex of three apolipoproteins and lipid that facilitates the transfer of lipids between ...
B J Blacklock, R O Ryan
doaj   +1 more source