Results 11 to 20 of about 280,160 (254)

Altered HDL particle in sickle cell disease: decreased cholesterol content is associated with hemolysis, whereas decreased Apolipoprotein A1 is linked to inflammation

open access: yesLipids in Health and Disease, 2019
Background Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of hemolysis, oxidative stress and ...
Ahmet Yalcinkaya   +2 more
doaj   +2 more sources

Lifestyle and Dietary Determinants of Serum Apolipoprotein A1 and Apolipoprotein B Concentrations: Cross-Sectional Analyses within a Swedish Cohort of 24,984 Individuals [PDF]

open access: goldNutrients, 2017
Low serum apolipoprotein (Apo) A1 concentrations and high serum ApoB concentrations may be better markers of the risk of cardiovascular disease than high-density lipoprotein (HDL) and low-density lipoprotein (LDL).
Kasper Frondelius   +5 more
openalex   +2 more sources

Evaluation of Serum Apolipoprotein A1 in Canine Sepsis [PDF]

open access: yesFrontiers in Veterinary Science, 2020
Decreased serum apolipoprotein A1 (Apo-A1) concentration is associated with mortality in human sepsis. The diagnostic and prognostic role of serum Apo-A1 concentrations in canine sepsis was evaluated.
M. Giunti   +4 more
semanticscholar   +5 more sources

Apolipoprotein A1 Levels Are Inversely Associated with Aneurysm Wall Enhancement in Unruptured Intracranial Aneurysms [PDF]

open access: yesNeurologia Medico-Chirurgica
Current magnetic resonance vessel wall imaging enables the detection of atherosclerotic changes in the walls of intracranial aneurysms. Lipid accumulation in the intracranial aneurysm wall is involved in aneurysm neovascularization and chronic ...
Masahiro HOSOGAI   +5 more
doaj   +2 more sources

Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype [PDF]

open access: greenMovement Disorders, 2014
ABSTRACTThe discovery of novel plasma‐based biomarkers could lead to new approaches in the treatment of Parkinson's disease (PD). Here, we explore the role of plasma apolipoprotein A1 (ApoA1) as a risk marker for PD and evaluate the influence of APOA1 promoter variation on plasma ApoA1 levels. Plasma ApoA1 and the single‐nucleotide polymorphism, rs670,
Christine R. Swanson   +15 more
openalex   +3 more sources

A Study of Serum Apolipoprotein A1, Apolipoprotein B and Lipid Profile in Stroke [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Background: Role of Serum Lipids, Lipoproteins and Lipoprotein related variables in the prediction of Stroke is less clear. Abnormalities in plasma Lipoproteins are the most firmly established and best understood risk factors for Atherosclerosis and ...
Shilpasree AS   +3 more
doaj   +3 more sources

Sex differences in apolipoprotein A1 and nevirapine‐induced toxicity [PDF]

open access: goldJournal of the International AIDS Society, 2014
Nevirapine (NVP) is associated with severe liver and skin toxicity through sulfotransferase (SULT) bioactivation of the phase I metabolite 12‐hydroxy‐NVP [1–3]. The female sex, a well‐known risk factor for NVP‐induced toxicity, is associated with higher SULT expression [4] and lower plasma levels of 12‐hydroxy‐NVP [3]. Interestingly, apolipoprotein A1 (
Aline T. Marinho   +7 more
openalex   +4 more sources

Apolipoprotein-A1 transports and regulates MMP2 in the blood. [PDF]

open access: yesNat Commun
Synthesized in the liver and intestines, apolipoprotein A1 (APOA1) transports cholesterol in high density lipoproteins from atherosclerotic lesions to the liver, protecting against atherosclerotic plaque rupture. Here, we show that proMMP2 (zymogen of matrix metalloproteinase-2) circulates associated with APOA1 in humans and APOA1-expressing mice. This
Sarker H   +11 more
europepmc   +4 more sources

High Apolipoprotein B/Apolipoprotein A1 is Associated with Vitamin D Deficiency Among Type 2 Diabetes Patients [PDF]

open access: yesDiabetes, Metabolic Syndrome and Obesity
Shuqi Wang,1,2 Haina Gao,3 Mengmeng Zhang,1,2 Shuchun Chen1,2 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Endocrinology, Hebei General Hospital, Shijiazhuang, People’s Republic of ...
Wang S, Gao H, Zhang M, Chen S
doaj   +2 more sources

Preoperative apolipoprotein B/apolipoprotein A1 ratio: a novel prognostic factor for gastric cancer

open access: yesOncoTargets and Therapy, 2018
Background The correlations between lipid profile (lipid molecules and their derivative indexes) and clinical outcome have been widely testified in many carcinomas, but its prognostic value remains unknown in gastric cancer (GC). Our purpose in the study
Ming-zhe Ma   +3 more
semanticscholar   +5 more sources

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