Results 31 to 40 of about 23,783 (200)

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +2 more sources

Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia

Annals of General Psychiatry, 2021
Background The apolipoprotein E (ApoE) gene polymorphisms are correlated with blood lipid levels and several neuropsychiatric symptoms. Therefore, this study aimed to examine whether the ApoE rs429358 affected the development and clinical symptoms of ...
Wenwang Rao, Xiangfei Meng, Keqing Li, Yunshu Zhang, Xiang Yang Zhang   +4 more
doaj   +1 more source

Assessment of causal association between differentiated thyroid cancer and disordered serum lipid profile: a Mendelian randomization study

Frontiers in Endocrinology, 2023
BackgroundResearch has shown that the disordered serum lipid profile may be associated with the risk of differentiated thyroid cancer (DTC). Whether this association reflect causal effect is still unclear.
Qiang Ma, Yu Li, Lijuan An, Liang Guo, Xiaokang Liu   +4 more
doaj   +1 more source

Apolipoproteins B and A1 in Ischemic Stroke Subtypes

Journal of Stroke and Cerebrovascular Diseases, 2020
Elevated serum apolipoprotein B and the apolipoprotein B/A1 ratio have been associated with ischemic stroke and intracranial atherosclerotic disease. We sought to assess the relationship between serum levels of apolipoprotein B, apolipoprotein A1, and the apolipoprotein B/A1 ratio with ischemic stroke subtypes and large artery atherosclerosis location ...
Rizwan Kalani, Soumya Krishnamoorthy, D. Deepa, Srinivas Gopala, Dorairaj Prabhakaran, David Tirschwell, P.N. Sylaja   +6 more
openaire   +3 more sources

Plasma proteome changes in cardiovascular disease patients: novel isoforms of apolipoprotein A1

Journal of Translational Medicine, 2011
Background The aim of this proteomic study was to look for changes taking place in plasma proteomes of patients with acute myocardial infarction (AMI), unstable angina pectoris (UAP), and stable angina pectoris (SAP).
Oravec Milan, Malý Martin, Suttnar Jiří, Reicheltová Zuzana, Májek Pavel, Pečánková Klára, Dyr Jan E   +6 more
doaj   +1 more source

Blood Lipid Biomarkers in Early Parkinson’s Disease and Parkinson’s Disease with Mild Cognitive Impairment

Journal of Parkinson’s Disease, 2022
Background: Lipid biomarkers have potential neuroprotective effects in Parkinson’s disease (PD) and there is limited evidence in the field. Objective: This study aims to investigate the association between comprehensive blood lipid biomarkers and PD ...
Xiao Deng, Seyed Ehsan Saffari, Samuel Yong Ern Ng, Nicole Chia, Jayne Yi Tan, Xinyi Choi, Dede Liana Heng, Zheyu Xu, Kay-Yaw Tay, Wing-Lok Au, Nan Liu, Adeline Ng, Eng-King Tan, Louis C.S. Tan   +13 more
doaj   +1 more source

Apolipoproteína A1 e litíase biliar na cirrose hepática.

Acta Médica Portuguesa, 1996
A prospective study was performed in 67 male patients with cirrhosis, admitted in our Department during one year. Biliary lithiasis was found in 37% of patients.
J Baranda, P Ministro, P Amaro, A Rosa, I Pimenta, A Donato, D De Freitas   +6 more
doaj   +1 more source

The relation between ApoB/ApoA-1 ratio and the severity of coronary artery disease in patients with acute coronary syndrome

The Egyptian Heart Journal, 2021
Background Apolipoprotein B is considered the primary protein constituent of low-density lipoprotein. LDL contains variable quantities of cholesterol, but each lipoprotein contains a single ApoB protein.
Rehab Ibrahim Yaseen, Mohamed Hesham El-Leboudy, Hend Mohammed El-Deeb   +2 more
doaj   +1 more source

Apolipoproteins and high-density lipoprotein phospholipids as indicators of atherosclerotic cardiovascular disease in Nigeria

African Journal of Laboratory Medicine
Background: Altered apolipoproteins and high-density lipoprotein (HDL) phospholipids are linked to premature atherosclerotic cardiovascular disease (ASCVD).
Promise C. Nwaejigh, Maria O. Ebesunun, Stephen S. Udofia, Adebusola A. Shakunle   +3 more
doaj   +1 more source

An abundant dysfunctional apolipoprotein A1 in human atheroma [PDF]

Nature Medicine, 2014
Recent studies have indicated that high-density lipoproteins (HDLs) and their major structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma are dysfunctional and are extensively oxidized by myeloperoxidase (MPO). In vitro oxidation of either apoA1 or HDL particles by MPO impairs their cholesterol acceptor function.
Huang, Ying, DiDonato, Joseph A., Levison, Bruce S., Schmitt, Dave, Li, Lin, Wu, Yuping, Buffa, Jennifer, Kim, Timothy, Gerstenecker, Gary, Gu, Xiaodong, Kadiyala, Chandra, Wang, Zeneng, Culley, Miranda K., Hazen, Jennie E., DiDonato, Anthony J., Fu, Xiaoming, Berisha, Stela, Peng, Daoquan, Nguyen, Truc, Liang, Shaohong, Chuang, Chia-Chi, Cho, Leslie, Plow, Edward F., Fox, Paul L., Gogonea, Valentin, Tang, W.H. Wilson, Parks, John S., Fisher, Edward A., Smith, Jonathan D., Hazen, Stanley L.   +29 more
openaire   +2 more sources