Results 11 to 20 of about 23,930 (202)

A Study of Serum Apolipoprotein A1, Apolipoprotein B and Lipid Profile in Stroke [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Role of Serum Lipids, Lipoproteins and Lipoprotein related variables in the prediction of Stroke is less clear. Abnormalities in plasma Lipoproteins are the most firmly established and best understood risk factors for Atherosclerosis and ...
Shilpasree AS, Savitri Sahukar, Jayaprakash Murthy, Kiran Kumar   +3 more
doaj   +3 more sources

Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer [PDF]

Frontiers in Pharmacology, 2019
Objective: Apolipoprotein A1 (ApoA1) is remarkably decreased in serum and ovarian tissues of ovarian cancer patients. ApoA1 and ApoA1 mimetic peptides can sequestrate pro-inflammatory phospholipids, some of which are known to activate a variety of ...
Aline T. Marinho, Aline T. Marinho, Haonan Lu, Sofia A. Pereira, Sofia A. Pereira, Emília Monteiro, Emília Monteiro, Hani Gabra, Chiara Recchi   +8 more
doaj   +5 more sources

Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. [PDF]

PLoS ONE, 2020
BackgroundSince 1920, a decrease in serum cholesterol has been identified as a marker of severe pneumonia. We have assessed the performance of serum apolipoprotein-A1, the main transporter of HDL-cholesterol, to identify the early spread of coronavirus ...
Thierry Poynard, Olivier Deckmyn, Marika Rudler, Valentina Peta, Yen Ngo, Mathieu Vautier, Sepideh Akhavan, Vincent Calvez, Clemence Franc, Jean Marie Castille, Fabienne Drane, Mehdi Sakka, Dominique Bonnefont-Rousselot, Jean Marc Lacorte, David Saadoun, Yves Allenbach, Olivier Benveniste, Frederique Gandjbakhch, Julien Mayaux, Olivier Lucidarme, Bruno Fautrel, Vlad Ratziu, Chantal Housset, Dominique Thabut, Patrice Cacoub   +24 more
doaj   +7 more sources

Association of Ratio of Apolipoprotein B to Apolipoprotein A1 With Survival in Peritoneal Dialysis

Frontiers in Nutrition, 2022
BackgroundAlthough the ratio of apolipoprotein B (apo B) to apolipoprotein A1 (apo A1) (apo B/apo A1) seems to be associated with mortality in hemodialysis (HD) patients, the association of apo B/apo A1 ratio with death remains not clear in peritoneal ...
Jing Yu, Jing Yu, Xi Xia, Xi Xia, Na-Ya Huang, Na-Ya Huang, Ya-Gui Qiu, Ya-Gui Qiu, Xiao Yang, Xiao Yang, Hai-Ping Mao, Hai-Ping Mao, Wei Chen, Wei Chen, Feng-Xian Huang, Feng-Xian Huang   +15 more
doaj   +3 more sources

Nanoengineering Apolipoprotein A1‐Based Immunotherapeutics [PDF]

Advanced Therapeutics, 2021
AbstractIn the slipstream of targeting the adaptive immune system, innate immunotherapy strategies are being developed. In this context, technologies based on natural carrier vehicles that inherently interact with the innate immune system, are increasingly being considered.
David P. Schrijver, Anne de Dreu, Stijn R. J. Hofstraat, Ewelina Kluza, Robby Zwolsman, Jeroen Deckers, Tom Anbergen, Koen de Bruin, Mirre M. Trines, Eveline G. Nugraha, Floor Ummels, Rutger J. Röring, Thijs J. Beldman, Abraham J. P. Teunissen, Zahi A. Fayad, Roy van der Meel, Willem J. M. Mulder   +16 more
openaire   +2 more sources

Apolipoprotein-A1 transports and regulates MMP2 in the blood. [PDF]

Nat Commun
Synthesized in the liver and intestines, apolipoprotein A1 (APOA1) transports cholesterol in high density lipoproteins from atherosclerotic lesions to the liver, protecting against atherosclerotic plaque rupture. Here, we show that proMMP2 (zymogen of matrix metalloproteinase-2) circulates associated with APOA1 in humans and APOA1-expressing mice. This
Sarker H, Panigrahi R, Lopez-Campistrous A, McMullen T, Reyes K, Anderson E, Krishnan V, Hernandez-Anzaldo S, Zheng XL, Glover JNM, Hardy E, Fernandez-Patron C.   +11 more
europepmc   +4 more sources

Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype [PDF]

Movement Disorders, 2014
ABSTRACTThe discovery of novel plasma‐based biomarkers could lead to new approaches in the treatment of Parkinson's disease (PD). Here, we explore the role of plasma apolipoprotein A1 (ApoA1) as a risk marker for PD and evaluate the influence of APOA1 promoter variation on plasma ApoA1 levels. Plasma ApoA1 and the single‐nucleotide polymorphism, rs670,
Christine R, Swanson, Katherine, Li, Travis L, Unger, Michael D, Gallagher, Vivianna M, Van Deerlin, Pinky, Agarwal, James, Leverenz, John, Roberts, Ali, Samii, Rachel Goldmann, Gross, Howard, Hurtig, Jacqueline, Rick, Daniel, Weintraub, John Q, Trojanowski, Cyrus, Zabetian, Alice S, Chen-Plotkin   +15 more
openaire   +2 more sources

Apolipoprotein A1 as a novel anti-implantation biomarker in polycystic ovary syndrome: A case-control study

Journal of Research in Medical Sciences, 2015
Background: Women with polycystic ovary syndrome have lower pregnancy rates, possibly due to the decreased uterine receptivity. Successful implantation depends on protein networks that are essential for cross-talk between the embryo and endometrium ...
Fatemehsadat Amjadi, Reza Aflatoonian, Shaghayegh Haghjoo Javanmard, Bita Saifi, Mahnaz Ashrafi, Mehdi Mehdizadeh   +5 more
doaj   +1 more source

The intestine as a source of apolipoprotein A1. [PDF]

Proceedings of the National Academy of Sciences, 1977
The major apoprotein of rat mesenteric lymph chylomicrons has been isolated and characterized and shown to be identical to apoprotein A1 (apo A1) isolated from serum high density lipoprotein (HDL). During intestinal lipid absorption, active synthesis of apo A1 was demonstrated by radioactive amino acid incorporation into lymph chylomicron A1 as well as
R M, Glickman, P H, Green
openaire   +2 more sources

Serum and urine apolipoprotien A1 (ApoA1) as biomarkers in bladder cancer [PDF]

Romanian Medical Journal
Bladder cancer (BC) is the predominant malignant neoplasm in the urinary system and ranks as the tenth most prevalent malignant tumor worldwide. Compared with females, males displayed a four-fold more common incidence of bladder cancer. It mainly affects
Farhan Hussien Khalaf, Manal Kamal Rasheed, Mohammed Bassil Ismail   +2 more
doaj   +1 more source