Results 31 to 40 of about 145,356 (331)

The molecular basis of truncated forms of apolipoprotein B in a kindred with compound heterozygous hypobetalipoproteinemia.

open access: yesJournal of Lipid Research, 1989
Krul et al. (1) have identified two truncated species of apolipoprotein B-100 in a kindred with familial hypobetalipoproteinemia. Five family members were identified who produce either one or both of two truncated apolipoprotein B-100 proteins estimated ...
P Talmud   +4 more
doaj   +1 more source

Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice

open access: yesJournal of Lipid Research, 1999
Over the past 10 years, many laboratories have investigated lipid metabolism and atherogenesis with a variety of transgenic and gene knockout mouse models.
Constance H. Zlot   +8 more
doaj   +1 more source

Apolipoprotein B-100 deficiency. Intestinal steatosis despite apolipoprotein B-48 synthesis. [PDF]

open access: yesJournal of Clinical Investigation, 1985
We describe a child, the issue of phenotypically normal parents, who had fat malabsorption, both intestinal and hepatic steatosis, and serum cholesterol and triglyceride concentrations of 38 and 63 mg/dl, respectively. Lipoprotein electrophoresis, Ouchterlony double diffusion, and electron microscopy demonstrated that normal low density lipoproteins ...
P N, Herbert   +7 more
openaire   +2 more sources

Rapid turnover of apolipoprotein C-III-containing triglyceride-rich lipoproteins contributing to the formation of LDL subfractionss⃞

open access: yesJournal of Lipid Research, 2007
The atherogenicity theory for triglyceride-rich lipoproteins (TRLs; VLDL + intermediate density lipoprotein) generally cites the action of apolipoprotein C-III (apoC-III), a component of some TRLs, to retard their metabolism in plasma.
Zheng Chunyu   +3 more
doaj   +1 more source

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism [PDF]

open access: yes, 2018
Table S1. Demographic and clinical features of human subjects used in this study. Figure S1. Aβ deposition in microvessels in AD patients and APPSw/0 mice. Figure S2. Biochemical analysis of Aβ42 aggregates. Figure S3.
Herz, Joachim   +9 more
core   +3 more sources

High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins

open access: yesJournal of Lipid Research, 2005
Efforts to elucidate the role of lipoprotein [a] (Lp[a]) in atherogenesis have been hampered by the lack of an animal model with high plasma Lp[a] levels.
Matthias Schneider   +11 more
doaj   +1 more source

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

open access: yes, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Alber, KF   +9 more
core   +1 more source

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans

open access: yesJournal of Lipid Research, 2003
Subjects with high plasma cholesterol levels exhibit a high production of VLDL apolipoprotein B-100 (apoB-100), suggesting that cholesterol is a mediator for VLDL production.
Berthil H.C.M.T. Prinsen   +8 more
doaj   +1 more source

Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. [PDF]

open access: yesJournal of Clinical Investigation, 1981
In the two genetic forms of abetalipoproteinemia described previously, recessive abetalipoproteinemia and homozygous hypobetalipoproteinemia, all lipoproteins that normally contain apolipoprotein B are absent from plasma. We describe here a new disorder in which normal low density and very low density lipoproteins are absent, but in which triglycerides
M J, Malloy   +4 more
openaire   +2 more sources

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