Results 41 to 50 of about 77,676 (146)
In vivo kinetics of apoB were performed in three apoB-67/apoB-100 heterozygotes using a primed-constant infusion of (5,5,5-(2)H3)-leucine. Mean plasma VLDL and LDL apoB-67 concentrations were 0.05 +/- 0.01 mg/dl and 0.62 +/- 0.17 mg/dl, respectively ...
F K Welty +5 more
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Distribution, transport, and degradation of apolipoprotein B-100 in HepG2 cells
The transport of apolipoprotein B (apoB) between the endoplasmic reticulum (ER) and Golgi was studied in puromycin-synchronized HepG2 cells, using an antibody that could distinguish between apoB in ER and Golgi compartments.
Nobuhiro Sakata +2 more
doaj +1 more source
Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation.
Apolipoprotein B is the principal protein associated with cholesterol transport in the blood and has been proposed to play a central role in human atherogenesis.
J M Hoeg +5 more
doaj +1 more source
Apolipoprotein-B-48 is a structural protein exclusively associated with post-prandial lipoproteins (chylomicrons). Apolipoprotein B-48 would be a useful marker to monitor the kinetics of chylomicrons in vivo, however, its quantitation is limited because ...
S D Proctor, J C Mamo
doaj +1 more source
Presence of two forms of apolipoprotein B in patients with dyslipoproteinemia.
Current information suggests that the major forms of the human B apolipoproteins, B-100 and B-48, are under separate genetic control and are synthesized by the liver and intestine, respectively. The apolipoprotein B composition of plasma lipoproteins has
M S Meng +4 more
doaj +1 more source
We describe here two patients, M. P. and S. L., with recessive abetalipoproteinemia. Analysis of restriction fragments of DNA from both patients using cDNA probes spanning the entire apolipoprotein B gene revealed no major insertions or deletions ...
ME Bouma +9 more
doaj +1 more source
Sixteen hyperlipidemic men were enrolled in a randomized, placebo-controlled, double-blind, cross-over study to evaluate the effect of ezetimibe 10 mg and simvastatin 40 mg, coadministered and alone, on the in vivo kinetics of apolipoprotein (apo) B-48 ...
André J Tremblay +3 more
doaj +1 more source
The Relationship between Levels of Lipids and Lipoprotein B-100 in Maternal Serum and Umbilical Cord Serum and Assessing Their Effects on Newborn Infants Anthropometric Indices [PDF]
Background & aim: This study aimed to determine the relationship between lipid and apolipoprotein B-100 (apo B-100) levels in maternal and umbilical cord sera as well as the effects of these components on anthropometric measurements of newborn infants ...
Ashraf Ghiasi +2 more
doaj
We have investigated the hypothesis that apolipoprotein B undergoes a regulated process of translocation into the endoplasmic reticulum (ER) which causes the protein to adopt a transmembrane configuration.
J M Leiper +4 more
doaj +1 more source
Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men
The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined ...
Sophie Desroches +7 more
doaj +1 more source

