Results 41 to 50 of about 77,676 (146)

Production of apolipoprotein B-67 in apolipoprotein B-67/B-100 heterozygotes: technical problems associated with leucine contamination in stable isotope studies

open access: yesJournal of Lipid Research, 1997
In vivo kinetics of apoB were performed in three apoB-67/apoB-100 heterozygotes using a primed-constant infusion of (5,5,5-(2)H3)-leucine. Mean plasma VLDL and LDL apoB-67 concentrations were 0.05 +/- 0.01 mg/dl and 0.62 +/- 0.17 mg/dl, respectively ...
F K Welty   +5 more
doaj   +1 more source

Distribution, transport, and degradation of apolipoprotein B-100 in HepG2 cells

open access: yesJournal of Lipid Research, 2001
The transport of apolipoprotein B (apoB) between the endoplasmic reticulum (ER) and Golgi was studied in puromycin-synchronized HepG2 cells, using an antibody that could distinguish between apoB in ER and Golgi compartments.
Nobuhiro Sakata   +2 more
doaj   +1 more source

Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation.

open access: yesJournal of Lipid Research, 1988
Apolipoprotein B is the principal protein associated with cholesterol transport in the blood and has been proposed to play a central role in human atherogenesis.
J M Hoeg   +5 more
doaj   +1 more source

Separation and quantification of apolipoprotein B-48 and other apolipoproteins by dynamic sieving capillary electrophoresis

open access: yesJournal of Lipid Research, 1997
Apolipoprotein-B-48 is a structural protein exclusively associated with post-prandial lipoproteins (chylomicrons). Apolipoprotein B-48 would be a useful marker to monitor the kinetics of chylomicrons in vivo, however, its quantitation is limited because ...
S D Proctor, J C Mamo
doaj   +1 more source

Presence of two forms of apolipoprotein B in patients with dyslipoproteinemia.

open access: yesJournal of Lipid Research, 1983
Current information suggests that the major forms of the human B apolipoproteins, B-100 and B-48, are under separate genetic control and are synthesized by the liver and intestine, respectively. The apolipoprotein B composition of plasma lipoproteins has
M S Meng   +4 more
doaj   +1 more source

Description of two different patients with abetalipoproteinemia: synthesis of a normal-sized apolipoprotein B-48 in intestinal organ culture.

open access: yesJournal of Lipid Research, 1990
We describe here two patients, M. P. and S. L., with recessive abetalipoproteinemia. Analysis of restriction fragments of DNA from both patients using cDNA probes spanning the entire apolipoprotein B gene revealed no major insertions or deletions ...
ME Bouma   +9 more
doaj   +1 more source

Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia

open access: yesJournal of Lipid Research, 2009
Sixteen hyperlipidemic men were enrolled in a randomized, placebo-controlled, double-blind, cross-over study to evaluate the effect of ezetimibe 10 mg and simvastatin 40 mg, coadministered and alone, on the in vivo kinetics of apolipoprotein (apo) B-48 ...
André J Tremblay   +3 more
doaj   +1 more source

The Relationship between Levels of Lipids and Lipoprotein B-100 in Maternal Serum and Umbilical Cord Serum and Assessing Their Effects on Newborn Infants Anthropometric Indices [PDF]

open access: yesJournal of Midwifery & Reproductive Health, 2014
Background & aim:  This study aimed to determine the relationship between lipid and apolipoprotein B-100 (apo B-100) levels in maternal and umbilical cord sera as well as the effects of these components on anthropometric measurements of newborn infants ...
Ashraf Ghiasi   +2 more
doaj  

Systematic expression of the complete coding sequence of apoB-100 does not reveal transmembrane determinants

open access: yesJournal of Lipid Research, 1996
We have investigated the hypothesis that apolipoprotein B undergoes a regulated process of translocation into the endoplasmic reticulum (ER) which causes the protein to adopt a transmembrane configuration.
J M Leiper   +4 more
doaj   +1 more source

Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men

open access: yesJournal of Lipid Research, 2004
The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined ...
Sophie Desroches   +7 more
doaj   +1 more source

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