Results 1 to 10 of about 73,331 (301)

Apolipoprotein C-II Deposition Amyloidosis: A Potential Misdiagnosis as Light Chain Amyloidosis [PDF]

Case Reports in Nephrology, 2016
Hereditary amyloidoses are rare and pose a diagnostic challenge. We report a case of hereditary amyloidosis associated with apolipoprotein C-II deposition in a 61-year-old female presenting with renal failure and nephrotic syndrome misdiagnosed as light ...
Sadichhya Lohani, Emily Schuiteman, Lohit Garg, Dhiraj Yadav, Sami Zarouk   +4 more
doaj   +3 more sources

Cardiovascular Disease Risk in Children With Chronic Kidney Disease: Impact of Apolipoprotein C-II and Apolipoprotein C-III [PDF]

Frontiers in Pediatrics, 2021
Cardiovascular disease (CVD) is an evolving process that begins in the early stages of chronic kidney disease (CKD) in children. Several surrogate markers, such as ambulatory blood pressure monitoring (ABPM), left ventricular (LV) mass, and arterial ...
Wei-Ling Chen, You-Lin Tain, Hung-En Chen, Chien-Ning Hsu, Chien-Ning Hsu   +4 more
doaj   +2 more sources

Apolipoprotein C‐II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway [PDF]

Clinical and Translational Medicine, 2021
Background Peritoneal metastasis (PM) occurs frequently in patients with gastric cancer (GC) and confers poor survival. Lipid metabolism acts as a non‐negligible regulator in epithelial–mesenchymal transition (EMT), which is crucial for the metastasis of
Chao Wang, Zhi Yang, En Xu, Xiaofei Shen, Xingzhou Wang, Zijian Li, Heng Yu, Kai Chen, Qiongyuan Hu, Xuefeng Xia, Song Liu, Wenxian Guan   +11 more
doaj   +2 more sources

Apolipoprotein C-II deficiency: detection of immunoreactive apolipoprotein C-II in the intestinal mucosa of two patients

Journal of Lipid Research, 1988
Recent data suggest that mutant immunoreactive forms of apolipoprotein C-II (apoC-II) can be detected in the plasma of patients with the apoC-II deficiency syndrome.
A Capurso, A M Mogavero, F Resta, M Di Tommaso, P Taverniti, F Turturro, M La Rosa, S Marcovina, A L Catapano   +8 more
doaj   +4 more sources

Lactylated Apolipoprotein C‐II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis [PDF]

Advanced Science
Mortality rates due to lung cancer are high worldwide. Although PD‐1 and PD‐L1 immune checkpoint inhibitors boost the survival of patients with non‐small‐cell lung cancer (NSCLC), resistance often arises. The Warburg Effect, which causes lactate build‐up
Jian Chen, Deping Zhao, Yupeng Wang, Ming Liu, Yuan Zhang, Tingting Feng, Chao Xiao, Huan Song, Rui Miao, Li Xu, Hongwei Chen, Xiaoying Qiu, Yi Xu, Jingxuan Xu, Zelin Cui, Wei Wang, Yanchun Quan, Yifeng Zhu, Chen Huang, Song Guo Zheng, Jian‐yuan Zhao, Ting Zhu, Lianhui Sun, Guangjian Fan   +23 more
doaj   +2 more sources

Apolipoprotein C-II Deficiency with Encephalopathy

Pediatric Neurology Briefs, 2003
Two siblings with severe hyperchylomicronemia and encephalopathy in early infancy are reported from Starship Children’s Hospital, Aukland, New Zealand.
J Gordon Millichap
doaj   +4 more sources

Apolipoprotein Profiles in Very Preterm and Term‐Born Preschool Children

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Little is known about plasma apolipoprotein profiles in very preterm‐born and term‐born preschool children compared with the adult population.
Anna Posod, Raimund Pechlaner, Xiaoke Yin, Sean Anthony Burnap, Sophia Julia Kiechl, Johann Willeit, Joseph L. Witztum, Manuel Mayr, Stefan Kiechl, Ursula Kiechl‐Kohlendorfer   +9 more
doaj   +2 more sources

Apolipoprotein C-II: a new look at an old protein. [PDF]

Eur Heart J, 2023
Hegele RA.
europepmc   +3 more sources

Identification of disulfide-linked apolipoprotein species in human lipoproteins

Journal of Lipid Research, 1993
We wished to determine whether apolipoprotein C-IIToronto, a mutant form of apolipoprotein C-II that contains a C-terminal cysteine residue, exists as a monomeric species or as multiple disulfide-linked species in plasma lipoproteins.
PW Connelly, GF Maguire, C Vezina, RA Hegele, JA Little   +4 more
doaj   +1 more source

Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis

Journal of Lipid Research, 2022
High levels of circulating triglycerides (TGs), or hypertriglyceridemia, are key components of metabolic diseases, such as type 2 diabetes, metabolic syndrome, and CVD.
Brynne E. Whitacre, Philip Howles, Scott Street, Jamie Morris, Debi Swertfeger, W. Sean Davidson   +5 more
doaj   +1 more source