Results 11 to 20 of about 73,331 (301)

Apolipoprotein A-II influences apolipoprotein E-linked cardiovascular disease risk in women with high levels of HDL cholesterol and C-reactive protein. [PDF]

PLoS ONE, 2012
BACKGROUND: In a previous report by our group, high levels of apolipoprotein E (apoE) were demonstrated to be associated with risk of incident cardiovascular disease in women with high levels of C-reactive protein (CRP) in the setting of both low ...
James P Corsetti, Stephan J L Bakker, Charles E Sparks, Robin P F Dullaart   +3 more
doaj   +3 more sources

The Circularization of Amyloid Fibrils Formed by Apolipoprotein C-II [PDF]

Biophysical Journal, 2003
Amyloid fibrils have historically been characterized by diagnostic dye-binding assays, their fibrillar morphology, and a "cross-beta" x-ray diffraction pattern. Whereas the latter demonstrates that amyloid fibrils have a common beta-sheet core structure, they display a substantial degree of morphological variation.
Hatters, D, MacRaild, C, Daniels, R, Gosal, W, Thomson, N, Jones, J, Davis, J, MacPhee, C, Dobson, C, Howlett, G   +9 more
openaire   +4 more sources

Amyloid fibrils formed by selective N-, C-terminal sequences of mouse apolipoprotein A-II [PDF]

, 2009
In mice, amyloidogenic type C apolipoprotein A-II (apoA-II) forms amyloid fibrils in age-associated amyloidosis. To understand the mechanism of amyloid fibril formation by apoA-II, we examined the polymerization of synthetic partial peptides of apoA-II ...
Tsutsumi-Yasuhara, Shinobu, Mori, Masayuki, Sawashita, Jinko, Higuchi, Keiichi, Yan, Jingmin, Naiki, Hironobu, Kametani, Fuyuki, Hasegawa, Kazuhiro, Zhang, Beiru   +8 more
core   +1 more source

Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels [PDF]

, 2003
The impact of common variants in the apolipoprotein gene cluster (APOC3-A4-A5) on prospective coronary heart disease (CHD) risk was examined in healthy UK men. Of the 2808 men followed over 9 years, 187 had a clinically defined CHD event.
Hawe, E., Miller, G.J., Hawe, Emma, Nicaud, V., Wong, W.-M.R., Wong, Wai-man R., Humphries, S.E., Li, Lai K., Li, L.K., Talmud, P.J., Nicaud, Viviane, Miller, George J., Pennacchio, Len A., Talmud, Philippa J., Pennacchio, L.A., Humphries, Steve E.   +15 more
core   +1 more source

A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency With Severe Triglyceridemia and Pancreatitis.

J Clin Endocrinol Metab, 2017
Context: Familial chylomicronemia syndrome (FCS) is a rare heritable disorder associated with severe hypertriglyceridemia and recurrent pancreatitis.
Ueda M, Dunbar RL, Wolska A, Sikora TU, Escobar MDR, Seliktar N, deGoma E, DerOhannessian S, Morrell L, McIntyre AD, Burke F, Sviridov D, Amar M, Shamburek RD, Freeman L, Hegele RA, Remaley AT, Rader DJ.   +17 more
europepmc   +2 more sources

Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene. [PDF]

, 2006
Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping this SNP.
Andrew T Hattersley, Venigalla, Prathyusha NS, Kirsten J Ward, Ward Kirsten J, Hattersley, Andrew T, Ward, Kirsten J, Giriraj R Chandak, Ellard Sian, Timothy M Frayling, Prathyusha NS Venigalla, Frayling, Timothy M, Sian Ellard, Chittaranjan S Yajnik, Hattersley Andrew T, Chandak Giriraj R, Frayling Timothy M, Yajnik Chittaranjan S, Chandak, Giriraj R, Venigalla Prathyusha NS, Ellard, Sian, Yajnik, Chittaranjan S   +20 more
core   +1 more source

High postprandial triglyceridemia in patients with type 2 diabetes and microalbuminuria

Journal of Lipid Research, 2007
Microalbuminuria (MA) is an independent risk factor for atherosclerosis in patients with type 2 diabetes mellitus (T2DM). Postprandial lipemia is also associated with excess cardiovascular risk.
Nicholas Tentolouris, Andreas Stylianou, Evangelia Lourida, Despoina Perrea, Despoina Kyriaki, Eleni C. Papavasiliou, Alexandros D. Tselepis, Nicholas Katsilambros   +7 more
doaj   +1 more source

Effect of Early Enteral Feeding on Apolipoprotein AI Levels and High-Density Lipoprotein Heterogeneity in Preterm Infants [PDF]

, 2001
Background/Aim: We have previously shown that infants receiving total parenteral nutrition have low apolipoprotein Al levels which are associated with high-density lipoprotein (HDL) class distributions as in lecithin:cholesterol acyltransferase ...
Berthold Koletzkob, Koletzko, Berthold, Yvonne Göbelb, Genzel-Boroviczény, Orsolya, Göbel, Yvonne, Orsolya Genzel-boroviczénya   +5 more
core   +1 more source

Primary structure of apolipoprotein A-II from inbred mouse strain BALB/c.

Journal of Lipid Research, 1987
The primary structure of apolipoprotein A-II (apoA-II) isolated from the plasma high density lipoprotein (HDL) fraction of the inbred mouse strain BALB/c is described in this work. The complete 78 amino acid protein sequence was determined by proteolytic
C G Miller, T D Lee, R C LeBoeuf, J E Shively   +3 more
doaj   +1 more source

Metabolism of C-apolipoproteins: kinetics of C-II, C-III1 and C-III2, and VLDL-apolipoprotein B in normal and hyperlipoproteinemic subjects.

Journal of Lipid Research, 1981
The turnover and metabolism of the individual C apolipoproteins (C-II, C-III1, and C-III2) were studied following the injection of 125I-labeled VLDL into 15 normal and hyperlipoproteinemic subjects. The C apolipoproteins from very low density lipoprotein
M W Huff, N H Fidge, P J Nestel, T Billington, B Watson   +4 more
doaj   +1 more source