Results 131 to 140 of about 121,670 (308)

Apolipoprotein-E forms dimers in human frontal cortex and hippocampus

, 2009
Background: Apolipoprotein-E (apoE) plays important roles in neurobiology and the apoE4 isoform increases risk for Alzheimer’s disease (AD). ApoE3 and apoE2 are known to form disulphide-linked dimers in plasma and cerebrospinal fluid whereas apoE4 cannot
David A Elliott (13483537), Brett Garner (20122005), Glenda M Halliday (4098229)   +2 more
core  

Cerebrospinal Fluid Apolipoprotein E Levels in Delirium

, 2017
Background/Aims: Delirium and the apolipoprotein E ε4 allele are risk factors for late-onset Alzheimer disease (LOAD), but the connection is unclear. We looked for an association.
Tai, J, Poljak, A ; https://orcid.org/, McVeigh, CL, Caplan, GA ; https://orcid.org/, JIan Tai, Gideon A. Caplan, Catherine L. McVeigh, Mark A. Hill, Anne Poljak, Fazrul Mohd Hanizan, Mohd Hanizan, F, Hill, MA   +11 more
core   +1 more source

Polymorphism of apolipoprotein E gene and atherosclerosis

Атеросклероз, 2008
Polymorphism genes assay is of importance for estimation of predisposition to multifactorial diseases on population and individual level. We investigated apolipoprotein E polymorphism and its influence on a lipid metabolism in population of Novosibirsk ...
M. I. Voevoda, E. V. Schakhtschneider, V. N. Maximov, I. V. Kulikov, A. G. Romaschenko   +4 more
doaj  

Apolipoprotein-D expression is increased during development and maturation of the human prefrontal cortex

, 2009
Apolipoprotein D (apoD) is a lipid binding protein expressed in the brain where its function is largely unknown. Based on changes in lipid metabolism and deposition that occur in the human brain during postnatal development, we investigated changes in ...
Cynthia Shannon Weickert (9138490), Jenny Wong (20119995), Sabine Bahn (15791), Brett Garner (20122005), Maree J Webster (20245149), Woojin S Kim (13601125)   +5 more
core  

Prevalência de fatores de risco cardiovasculares em adolescentes e associação da lipemia sérica com a variabilidade nos polimorfismos dos genes APOA5 e APOB, composição corporal e aptidão cardiorrespiratória em adolescentes e pais [PDF]

, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2011Objetivo: Verificar a prevalência de fatores de risco cardiovasculares em adolescentes e analisar a ...
Pelegrini, Andreia
core  

Association between apolipoprotein E gene polymorphism and mild cognitive impairment: a meta-analysis

, 2017
Yunxia Jiang,1,* Tao He,2,* Wenshuai Deng,2 Peng Sun2 1Nursing College of Qingdao University, Qingdao University, 2Department of Neurosurgery, Affiliated Hospital of Qingdao University, Qingdao, China *These authors contributed equally to this work ...
Jiang Y, He T, Sun P, Deng W
core  

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice

, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A, Owen, JS, Dickson, G, Graham, IR, Harris, JD   +4 more
core  

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Propofol‐induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This study aimed to assess the incidence and identify risk factors associated with the development of propofol‐induced hypertriglyceridemia in critically ill trauma patients who required nutrition therapy. Methods Adult patients (aged >17 years) admitted to the trauma intensive care unit who received propofol for >24 h and had a ...
Emma S. Lemke, Jonathon K. Walker, Julie E. Farrar, Saskya Byerly, Dina M. Filiberto, Roland N. Dickerson   +5 more
wiley   +1 more source