Results 161 to 170 of about 195,708 (344)

Analyzing the Role of Specific Damage-Associated Molecular Patterns-Related Genes in Osteoarthritis and Investigating the Association between β-Amyloid and Apolipoprotein E Isoforms

open access: yesJournal of Innate Immunity
Introduction: Osteoarthritis (OA) is a prevalent chronic joint disorder. It is characterized by an immune response that maintains a low level of inflammation throughout its progression.
Fangling Yuan   +3 more
doaj   +1 more source

Macrophage free cholesterol content regulates apolipoprotein E synthesis.

open access: hybrid, 1987
T Mazzone   +3 more
openalex   +1 more source

The Predictive Value of Quantitative Flow Ratio and Its Derived Angiographic Microvascular Resistance for Restenosis Following Drug‐Coated Balloon Angioplasty

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Initially, drug‐coated balloon (DCB) angioplasty was primarily employed for in‐stent restenosis (ISR) treatment. Over time, its indications have broadened to include de novo small‐vessel lesions and bifurcation lesions. However, there is a lack of effective strategies to reduce restenosis rates post‐DCB angioplasty.
Chenhang Wang, Li Chen, Xiaoyong Xu
wiley   +1 more source

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin   +5 more
wiley   +1 more source

The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding.

open access: hybrid, 1983
Karl H. Weisgraber   +6 more
openalex   +1 more source

HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background The ratio of high‐density lipoprotein cholesterol (HDL‐C) to low‐density lipoprotein cholesterol (LDL‐C) predicts cardiovascular disease (CVD) endpoints, yet its prognostic validity in high‐risk populations and for type 2 diabetes mellitus (T2DM)‐related adverse events remains unestablished. Methods This study included 32,609 people
Biting Lin   +10 more
wiley   +1 more source

Site-specific mutagenesis of human apolipoprotein E. Receptor binding activity of variants with single amino acid substitutions.

open access: hybrid, 1988
Avraham Lalazar   +9 more
openalex   +1 more source

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