Results 11 to 20 of about 194,689 (341)

LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit [PDF]

, 2011
Apolipoprotein A-I and Apolipoprotein E promote different steps of reverse cholesterol transport, including lecithin-cholesterol acyltransferase stimulation.
A. Carlucci, L. Cigliano, B. Maresca, M. S. Spagnuolo, G. Di Salvo, R. Calabrò, P. Abrescia   +6 more
core   +2 more sources

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]

, 2016
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core   +1 more source

Apolipoprotein Mimetic Peptides: A New Approach for the Treatment of Asthma

Frontiers in Pharmacology, 2012
New treatments are needed for severe asthmatics to improve disease control and avoid severe toxicities associated with oral corticosteroids. We have used a murine model of house dust mite (HDM)-induced asthma to identify steroid-unresponsive genes that ...
Xianglan eYao, Michael P. Vitek, Alan T. Remaley, Stewart J. Levine   +3 more
doaj   +1 more source

Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia

Annals of General Psychiatry, 2021
Background The apolipoprotein E (ApoE) gene polymorphisms are correlated with blood lipid levels and several neuropsychiatric symptoms. Therefore, this study aimed to examine whether the ApoE rs429358 affected the development and clinical symptoms of ...
Wenwang Rao, Xiangfei Meng, Keqing Li, Yunshu Zhang, Xiang Yang Zhang   +4 more
doaj   +1 more source

Apolipoprotein E gene polymorphism, serum lipids, and risk of superficial fungal infections in Egyptian patients – A preliminary case-controlled study

Indian Journal of Dermatology, 2023
Background: Apolipoprotein E (APOE) gene isoforms have been found to affect the risk of superficial fungal infections (SFIs). However, the data only cover a few ethnicities.
Amany I Mustafa, Ghada M Shams, Eman M Fawzy, Naglaa F Alhusseini, Rana A Khashaba, Ola S EL-Shimi   +5 more
doaj   +1 more source

Apolipoprotein E and renal disease [PDF]

American Journal of Kidney Diseases, 2004
Apolipoprotein E (ApoE) is a major constituent of plasma lipoproteins with many biological actions of great significance. Beyond the known influence of ApoE polymorphisms on serum lipid profile, the pathogenesis of atherosclerosis, and the development of neurodegenerative disorders, ApoE also has a major role in the pathogenesis and progression of a ...
Liberopoulos, E., Siamopoulos, K., Elisaf, M. S.   +2 more
openaire   +3 more sources

Apolipoprotein E related Co-Morbidities and Alzheimer’s disease [PDF]

, 2016
The primary goal of advancement in clinical services is to provide a health care system that enhances an individual’s quality of life. Incidence of diabetes mellitus, cardiovascular disease and associated dementia coupled with the advancing age of the ...
Akiyama, Alharbi, Armitage, Armitage, Armitage, Balin, Barbieri, Bergdahl, Berliner, Borilova Linhartova, Borrell-Pages, Bowling, Braak, Braak, Brown, Bu, Buchanan, Burt, Cambell, Cavrini, Chiu, Chukkapalli, Chukkapalli, Chukkapalli, Cole, Corder, Corrada, Curtiss, Cutler, De Oliveira, DeFronzo, DeStefano, Desvarieux, Duarte, Epel, Farrer, Forner, Foster, Freitag-Wolf, Galbraith, Gan, Gao, Genco, Grehan, Grossi, Habib, Haffajee, Hajishengalis, Hajishengalis, Haraszthy, Hardardottir, Hardy, Harold, Harper, Hayashi, Hayden, Heiduschka, Helfand, Het, Hitt, Holt, Hu, Huang, Hunter, Hutton, Imhof, Iqbal, Itzhaki, Jagannathachary, Joiner, Kamer, Kamer, Kamer, Katz, Khovidhunkit, Klein, Kliegel, Kolovou, Kornman, Kozarov, Kubota, Lalla, Lambert, Lesne, Leszcynska, Libby, Machado, Mahley, Mahley, Mahley, Mahley, Maney, Marti, McGeer, Michalowicz, Miklossy, Miklossy, Miller, Mooradian, Moutsopoulos, Nagpal, Neto, Nicoll, Noble, Okuda, Olsen, Ono, O’Brien, Papapanou, Perls, Pitas, Pizzo, Poirier, Poling, Poole, Poole, Rivera, Riviere, Rogers, Rohn, Roses, Roses, Rowe, Saito, Saunders, Scannapieco, Schuett, Shao, Singhrao, Singhrao, Singhrao, Singhrao, Small, Smit, Socransky, Soscia, Stein, Strittmatter, Strittmatter, Sullivan, Velsko, Walsh, Walsh, Watkins, Weisgraber, Wetterau, Wilson, Young   +147 more
core   +1 more source

Relationship between Apolipoprotein Superfamily and Parkinson's Disease

Chinese Medical Journal, 2017
Objective: Parkinson's disease (PD) is featured with motor disorder and nonmotor manifestations including psychological symptoms, autonomic nervous system dysfunction, and paresthesia, which results in great inconvenience to the patients' life.
Lin Li, Ming-Su Liu, Guang-Qin Li, Jie Tang, Yan Liao, Yang Zheng, Tong-Li Guo, Xin Kang, Mao-Ting Yuan   +8 more
doaj   +1 more source

Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity

Biomolecules, 2020
Apolipoprotein E (ApoE) has become a primary focus of research after the discovery of its strong linkage to Alzheimer’s disease (AD), where the ApoE4 variant is the highest genetic risk factor for this disease.
Anna L. Gharibyan, Tohidul Islam, Nina Pettersson, Solmaz A. Golchin, Johanna Lundgren, Gabriella Johansson, Mélany Genot, Nina Schultz, Malin Wennström, Anders Olofsson   +9 more
doaj   +1 more source

Lipids and apolipoproteins C-III and E among treatment-naïve and treatment-experienced persons with HIV in Nigeria

African Journal of Laboratory Medicine, 2023
Background: Dyslipidaemia is a known cause of cardiovascular mortality. Persons living with HIV are at high risk of developing cardiovascular disease due to lipid metabolism disorders associated with HIV or its therapy.
Mercy N. Okunorobo, Nwakasi K. Nnamah, Ugomma A. Ude, Enyioma A. Ude   +3 more
doaj   +1 more source