Results 201 to 210 of about 195,708 (344)

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

International Journal of Cancer, EarlyView.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello, Eric Felli, Teresa Musarra, Lorenzo Nevi, Annamaria Altomare, Jordi Gracia‐Sancho, Andrea Baiocchini, Simone Carotti   +7 more
wiley   +1 more source

Perceptual discrimination of complex objects: Apolipoprotein E e4 gene-dose effects in mid-life. [PDF]

Alzheimers Dement
Lancaster C, Berens S, Daly J, Rusted J, Bird CM.   +4 more
europepmc   +1 more source

Apolipoprotein E to B Ratio: A Marker for Type III Hyperlipoproteinaemia [PDF]

, 1993
Winfried März, Giso Feussner, R. Siekmeier, Bettina Donnerhak, Ludwig Schaaf, Viktor Růžička, Gross Wl   +6 more
openalex   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

iLABMED, EarlyView.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Association between Apolipoprotein E gene polymorphism and the tortuosity of extracranial carotid artery. [PDF]

Front Neurol
Wang JW, Li X, Lu LX, Chen JL, Yang YT, Jin G.   +5 more
europepmc   +1 more source

Development of an Artificial Intelligence Verification System Model for Clinical Biochemistry Laboratories Using Machine Learning

iLABMED, EarlyView.
The constructed AI verification system performed excellently in terms of accuracy and efficiency. This study provides a new solution for the intelligent verification of clinical biochemistry laboratories and has certain application value. ABSTRACT Background With the exponential growth of testing samples in clinical biochemistry laboratories ...
Lin Zhu, Jie Feng, Rong Zheng, Jianzhu Wang, Jin Dong, Jing Gao, Qiuliang Yang, Xuemei Wei, Hui Ding, Xu Zhang, Jinyao Ma, Jingzhao Mei, Yanhong Gao   +12 more
wiley   +1 more source

Longitudinal effects of sex differences and apolipoprotein E genotype on white matter engagement among elderly. [PDF]

Brain Commun
Zhang H, Zhang J, Hsu CL, Hui ES, Tse KH, Mak HK, Shum DHK.   +6 more
europepmc   +1 more source

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.

, 1990
Robert Kowal, Joachim Herz, Karl H. Weisgraber, R W Mahley, M S Brown, J L Goldstein   +5 more
openalex   +1 more source

Influence of apolipoprotein E polymorphism on apolipoprotein B-100 metabolism in normolipemic subjects. [PDF]

, 1991
Thomas Demant, Dorothy Bedford, Chris J. Packard, J Shepherd   +3 more
openalex   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source