Results 251 to 260 of about 19,002,199 (367)

Efficacy and safety of low‐dose atorvastatin plus ezetimibe for primary hypercholesterolemia: A randomized, double‐blind, multicenter phase 3 trial

Lipids, EarlyView.
Low‐dose atorvastatin combined with ezetimibe achieves superior LDL‐C reduction (44.8%) compared with equivalent or higher‐dose statin monotherapy in Korean patients, presenting a more effective and safer therapeutic strategy potentially applicable to broader Asian populations.
Tae Oh Kim, Kyounghoon Lee, Jin‐Man Cho, Hyuck‐Jun Yoon, Tae‐Ho Park, Jung Hyun Choi, Jung‐Won Suh, Seok‐Yeon Kim, Hong‐Seok Lim, Jong‐Seon Park, Deok‐Kyu Cho, Gyung‐Min Park, Sung‐Gyun Ahn, Sanghoon Shin, Sung Uk Kwon, Dae‐Hyeok Kim, Sang‐Rok Lee, Jung‐Hoon Sung, Hwan‐Cheol Park, Seung‐Whan Lee   +19 more
wiley   +1 more source

Impact of Apolipoprotein E Variants: A Review of Naturally Occurring Variants and Clinical Features. [PDF]

J Atheroscler Thromb
Matsunaga A, Saito T.
europepmc   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Preventive, ameliorative, and therapeutic effects of steamed mature silkworms on metabolic disorders caused by loss of apolipoprotein E. [PDF]

NPJ Sci Food
Nguyen MAH, Nguyen TTT, Kim YH, Koh YH.
europepmc   +1 more source

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

Nature, 2012
R. Bell, E. Winkler, I. Singh, A. Sagare, R. Deane, Zhenhua Wu, D. Holtzman, C. Betsholtz, A. Armulik, J. Sallstrom, B. Berk, B. Zlokovic   +11 more
semanticscholar   +1 more source

Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients

Molecular Carcinogenesis, EarlyView.
ABSTRACT Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation‐induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a ...
Fengyuan Yu, Zheng Gong, Yuan Li, Danial F. Naseem, Chen Li, Miaowei Wen, Bingying Zhao, Zhezhe Xu, Shanshan Zhang, Rukun Zang, Ailu Wu, Qingxin Han, Shuhui Wu, Hongwei Li, Yipeng Song   +14 more
wiley   +1 more source

Apolipoprotein E-4Philadelphia (Glu13—-Lys,Arg145—-Cys). Homozygosity for two rare point mutations in the apolipoprotein E gene combined with severe type III hyperlipoproteinemia

, 1991
P Lohse, W. Alexander Mann, Eric A. Stein, H. Bryan Brewer   +3 more
openalex   +1 more source

Evidence of Involvement of the Calcitonin Gene‐Related Peptide in Restless Legs Syndrome

Movement Disorders, EarlyView.
Abstract Background Restless legs syndrome (RLS) is a common sensory‐motor disorder characterized by an urge to move the legs, often with unpleasant sensations, particularly during rest. Current treatments include iron supplementation, dopamine agonists, and opioids, but new therapeutic approaches are needed.
Maria P. Mogavero, Mojibola Fowowe, Akeem Sanni, Mona Goli, Giuseppe Lanza, Francesca L'Episcopo, Luigi Ferini‐Strambi, Yehia Mechref, Raffaele Ferri   +8 more
wiley   +1 more source

Impact of Apolipoprotein E ε4 in Alzheimer's Disease: Insights From a Meta-Analysis. [PDF]

J Clin Neurol
Kwon HS, Koh SH.
europepmc   +1 more source

Associations Between Lipids and Lipid‐Lowering Drug Target Genes and Osteomyelitis: A Mendelian Randomization Analysis

Medicine Advances, EarlyView.
In this study, we identified several SNPs in PCSK9 as genetic tools to comprehensively assess the influential role of PCSK9 in CHD, CRP, and osteomyelitis. PCSK9 is associated with a lower risk of osteomyelitis, and PCSK9 is also associated with a reduction in CRP concentrations. Our study supports the notion that WC may be a potential mediator between
Zhiyi Zhou, Zhehan Yang, Junpan Chen, Minghao Wen, Jiayuan Lei, Wanzhe Liao, Yahan Li, Linghui Liu, Ziyuan Lu   +8 more
wiley   +1 more source