Results 251 to 260 of about 20,685,408 (374)

The Next Frontier: Micro/Nanorobots Operating Inside the Living Body

SmartBot, EarlyView.
Micro/nanorobots, with their tiny size and controllable motion capabilities, can perform complex and precise tasks in micro‐spaces, thus showing broad application prospects in the biomedical field. This review systematically summarizes the core advantages of micro/nanorobots in real‐time in vivo imaging, targeted drug delivery, and active barrier ...
Ningbo Yu, Jie Yang, Zicheng Ni, Yuepeng Cai, Beatriz Jurado‐Sánchez, Renfeng Dong   +5 more
wiley   +1 more source

Toll-like receptor 9 promotes aortic chondrogenesis and calcification in apolipoprotein E-deficient mice. [PDF]

Heart Vessels
Bando R, Hara T, Maeda J, Bavuu O, Fukuda D, Sata M.   +5 more
europepmc   +1 more source

The role of RNA editing in cancer development and metabolic disorders [PDF]

, 2018
Kung, Che-Pei, Maggi, Leonard B, Jr., Weber, Jason D   +2 more
core   +2 more sources

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source

Lecanemab for treatment of individuals with early Alzheimer's Disease (AD) who are apolipoprotein E ε4 (ApoE ε4) non-carriers or heterozygotes. [PDF]

J Prev Alzheimers Dis
Perry R, Kipps C, Soto Martín ME, Bozzali M, Logroscino G, Trafford S, Dhadda S, Kanekiyo M, Goodwin A, Hodgkinson M, Hersch S, Irizarry M, Kramer L, Froelich L.   +13 more
europepmc   +1 more source

Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses’ Health Study

, 2019
Iris Y. Kim, Francine Grodstein, Peter Kraft, Gary C. Curhan, Katherine C. Hughes, Hongyan Huang, Jae H. Kang, David J. Hunter   +7 more
openalex   +2 more sources

Insulin resistance, dyslipidemia, and apolipoprotein E interactions as mechanisms in cognitive impairment and Alzheimer's disease

Experimental biology and medicine, 2016
Therese S Salameh, E. Rhea, W. Banks, A. Hanson   +3 more
semanticscholar   +1 more source

Unilateral mastication‐induced memory deficits linked to disrupted hippocampal cholesterol metabolism in rats

VIEW, EarlyView.
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai, Yifan Hu, Rongchen Xu, Xinyu Xu, Bowen Ma, Dongzong Huang, Hongchen Liu, Hongbo Li, Yuan Hu, Hua Jiang   +9 more
wiley   +1 more source

Apolipoprotein E ɛ3/ɛ4 genotype is associated with premature myocardial infarction: a hospital based retrospective study. [PDF]

BMC Cardiovasc Disord
Wang H, Li B, Chen W, Wei G, Chen K, Wang W, Liu Y.   +6 more
europepmc   +1 more source

Polymorphisms of the ApoE (Apolipoprotein E) Gene and Their Influence on Dyslipidemia in HIV-1-Infected Individuals

, 2014
Tanida Suwalak, Pornpen Srisawasdi, Apichaya Puangpetch, Siwalee Santon, Napatrupron Koomdee, Monpat Chamnanphon, Angkana Charoenyingwattana, Wasun Chantratita, Chonlaphat Sukasem   +8 more
openalex   +2 more sources