Results 51 to 60 of about 20,685,408 (374)

Apolipoprotein E Gene Polymorphism and Coronary Artery Disease Risk Among Patients in Northwest China

Pharmacogenomics and Personalized Medicine, 2021
Wenbing Ma,1,2 Xiaodong Ren,1 Liting Zhang,1 Haiyan Dong,1 Xiaoyun Lu,2 Weiyi Feng1 1Department of Pharmacology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Department of Biological ...
Ma W, Ren X, Zhang L, Dong H, Lu X, Feng W   +5 more
doaj  

Predictive capability of Cys112Arg single nucleotide polymorphisms of the apolipoprotein E gene in assessing the risk of immediate and early post-traumatic seizures

Терапевтический архив, 2023
This study is aimed at investigating epileptic seizures, one of the consequences of traumatic brain injury (TBI). Immediate and early post-traumatic seizures, as well as late post-traumatic epileptic seizures or post-traumatic epilepsy, can have ...
Kseniia K. Kriukova, Evgenia V. Alexandrova, Olga N. Voskresenskaya, Vitaliy V. Podlepich, Alexander D. Kravchuk, Eric I. Rytkin, Yaroslav A. Latyshev, Dmitry A. Kudlay, Susanna S. Sologova, Sabr A. Albagachiev, Mark A. Mandrik   +10 more
doaj   +1 more source

The impact of dementia, age and sex on category fluency: Greater deficits in women with Alzheimer's disease [PDF]

, 2008
Original article can be found at: http://www.sciencedirect.com/science/journal/00109452 Copyright Elsevier Masson DOI: 10.1016/j.cortex.2007.11.008A category specific effect in naming tasks has been reported in patients with Alzheimer's dementia ...
Laws, K.R., Moreno-Martinez, F.J., Schulz, J.   +2 more
core   +1 more source

Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins

Journal of Lipid Research, 2012
Mipomersen, an antisense oligonucleotide that reduces hepatic production of apoB, has been shown in phase 2 studies to decrease plasma apoB, LDL cholesterol (LDL-C), and triglycerides.
Jeremy D. Furtado, Mark K. Wedel, Frank M. Sacks   +2 more
doaj   +1 more source

Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]

, 2019
Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde, De Bruyne, Sander, Delanghe, Joris, Delanghe, Sigurd, Speeckaert, Marijn, Van Biesen, Wim   +5 more
core   +1 more source

Apolipoprotein E-related glomerular disorders.

Kidney International, 2019
Of the glomerular disorders that occur due to apolipoprotein E (apoE) mutations, apoE2 homozygote glomerulopathy and lipoprotein glomerulopathy (LPG) have been characterized.
Takao Saito, A. Matsunaga, M. Fukunaga, K. Nagahama, S. Hara, E. Muso   +5 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Expression of apolipoprotein E by cultured vascular smooth muscle cells is controlled by growth state. [PDF]

, 1988
Rat vascular smooth muscle cells (SMC) in culture synthesize and secrete a approximately 38,000-Mr protein doublet or triplet that, as previously described (Majack and Bornstein. 1984. J. Cell Biol.
Castle, CK, Gebicke-Haerter, PJ, Goodman, LV, Mahley, RW, Majack, RA, Shooter, EM, Weisgraber, KH   +6 more
core   +1 more source

PECAM‐1 directed re‐targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E‐mediated uptake

Journal of Controlled Release, 2018
Systemic administration of lipid nanoparticle (LNP)‐encapsulated messenger RNA (mRNA) leads predominantly to hepatic uptake and expression. Here, we conjugated nucleoside‐modified mRNA‐LNPs with antibodies (Abs) specific to vascular cell adhesion ...
H. Parhiz, V. Shuvaev, N. Pardi, M. Khoshnejad, R. Kiseleva, J. Brenner, Thomas Uhler, Steven Tuyishime, B. Mui, Ying K. Tam, T. D. Madden, M. Hope, D. Weissman, V. Muzykantov   +13 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source