Results 1 to 10 of about 52,991 (293)
Diagnostic and pathogenetic significance of apolipoprotein disorders in patients with alcoholic fatty liver [PDF]
Vojnosanitetski Pregled, 2017 Background/Aim. Alcohol is the most common cause of fatty liver. Alcohol metabolism takes place in the liver by alcohol dehydrogenase, to toxic acetaldehyde, with fatty acids accumulation in the liver as a consequence.
Mladenović Bojan +3 more
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Lipids in Health and Disease, 2023 Background & aims Apolipoproteins and lipoprotein(a) are associated with various cardiometabolic diseases, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, among others.
Juan R. Ulloque-Badaracco +8 more
doaj +1 more source
Apolipoprotein A-I mimetics [PDF]
Current Opinion in Lipidology, 2014 To summarize recent publications in the field of apolipoprotein mimetics.Apolipoprotein mimetic peptides continue to show efficacy in a number of animal models of disease and demonstrate properties that make them attractive as potential therapeutic agents. A number of new apolipoprotein mimetics have been described recently.
Reddy, Srinivasa T +3 more
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Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses. [PDF]
PLoS ONE, 2015 Apolipoprotein E (ApoE), an exchangeable apolipoprotein, is necessary for production of infectious Hepatitis C virus (HCV) particles. However, ApoE is not the only liver-expressed apolipoprotein and the role of other apolipoproteins for production of ...
Kathrin Hueging +11 more
doaj +1 more source
Journal of Lipid Research, 2022 Lipoprotein(a) [Lp(a)] concentrations are regulated by the LPA gene mainly via the large kringle IV-type 2 (KIV-2) copy number variation and multiple causal variants.
Rebecca Grüneis +10 more
doaj +1 more source
ApoPred: Identification of Apolipoproteins and Their Subfamilies With Multifarious Features
Frontiers in Cell and Developmental Biology, 2021 Apolipoprotein is a group of plasma proteins that are associated with a variety of diseases, such as hyperlipidemia, atherosclerosis, Alzheimer’s disease, and diabetes.
Ting Liu +7 more
doaj +1 more source
Smoking and apolipoprotein levels: A meta-analysis of published data
Toxicology Reports, 2022 Background: Apolipoproteins are major components of lipoproteins such as high-density lipoprotein (HDL) and very-low-density lipoprotein and are considered nontraditional markers in the risk assessment for cardiovascular disease.
Alba Romero Kauss +6 more
doaj +1 more source
Apolipoprotein A‐I induced amyloidosis [PDF]
FEBS Letters, 1998 Amyloidosis is characterized by extracellular deposits of protein fibrils with a high content of β‐sheets in secondary structure. The protein forms together with proteoglycans amyloid fibrils causing organ damage and serious morbidity. Intact apolipoprotein A‐I (apoA‐I) is an important protein in lipid metabolism regulating the synthesis and catabolism
Genschel, Janine +3 more
openaire +2 more sources
The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
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The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations [PDF]
Twin Research, 2000 AbstractThe effects of apolipoprotein (a), apolipoprotein-E, and apolipoprotein-A4 isoforms on quantitative lipoprotein(a) [Lp(a)] levels were assessed in a sample of 142 Dutch families consisting of two parents and their adolescent twin offspring. A total heritability of 95% was estimated for plasma Lp(a) concentrations.
Boomsma, D. I. +6 more
openaire +4 more sources