Results 21 to 30 of about 43,955 (304)

ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions

Journal of Lipid Research, 2003
ATP binding cassette transporter A1 (ABCA1) mediates the transport of phospholipids and cholesterol from cells to lipid-poor HDL apolipoproteins. Cholesterol loading of cells induces ABCA1, implicating cholesterol as its major physiologic substrate.
Ashley M. Vaughan, John F. Oram
doaj   +1 more source

The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function.

Journal of Lipid Research, 1992
Site-directed mutagenesis and other molecular biology-based techniques are now available for probing the amphipathic alpha helix structural motif in the exchangeable apolipoproteins. Here we survey the published literature on lipid-binding and functional
JP Segrest, MK Jones, H De Loof, CG Brouillette, YV Venkatachalapathi, GM Anantharamaiah   +5 more
doaj   +1 more source

The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]

, 1981
Peer ...
Giesemann, G., Müller, O. A., Scriba, Peter Christian, Stalla, G., Wood, W. G.   +4 more
core   +2 more sources

Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma[S]

Journal of Lipid Research, 2019
Apolipoproteins are major structural and functional constituents of lipoprotein particles. As modulators of lipid metabolism, adipose tissue biology, and energy homeostasis, apolipoproteins may serve as biomarkers or potential therapeutic targets for ...
Richard Wagner, Julia Dittrich, Joachim Thiery, Uta Ceglarek, Ralph Burkhardt   +4 more
doaj   +1 more source

The effect of 17β-estradiol plus norethisterone acetate treatment on lipoprotein (a), atherogenic and anti-atherogenic apolipoproteins levels in postmenopausal women: A meta-analysis of randomized controlled trials

Experimental Gerontology, 2023
Background and aim: The administration of 17β-estradiol plus norethisterone acetate seems to confer women cardioprotection, however, its impact on lipoprotein (a) and apolipoproteins' concentrations remains unclear.
Zengyao Tang, Mihnea-Alexandru Găman, Kousalya Prabahar, HanYing Mei   +3 more
doaj   +1 more source

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]

, 2008
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn, Boyles, Boyles, Butterfield, D. W. Walker, Desai, Do Carmo, Duffy, Guti  rrez, J. Muffat, Kalman, Lechner, Morais Cabral, Navarro, Oakley, Pfaffl, Provost, Provost, Rassart, S. Benzer, Sanchez, Sutcliffe, Terrisse, Thomas, Thomas, Toroser, Vogt, Walker, Wallace, Walsh, Weech   +30 more
core   +3 more sources

Degradation of human apolipoprotein B‐100 by apolipoprotein(a)

FEBS Letters, 1993
Human plasma low density lipoproteine (LDL) contain a very high molecular weight protein termed apoB‐100 (M r = 550,000). In many samples of LDL, minor components designated as apoB‐74 (M r = 407,000) and apoB‐26 (M r = 145,000) are present. It has been shown that they can arise as a result of proteolytic degradation of apoB‐100.
Chulkova, T.M., Tertov, V.V.
openaire   +2 more sources

Reconfiguring Nature’s Cholesterol Accepting Lipoproteins as Nanoparticle Platforms for Transport and Delivery of Therapeutic and Imaging Agents

Nanomaterials, 2020
Apolipoproteins are critical structural and functional components of lipoproteins, which are large supramolecular assemblies composed predominantly of lipids and proteins, and other biomolecules such as nucleic acids.
Skylar T. Chuang, Siobanth Cruz, Vasanthy Narayanaswami   +2 more
doaj   +1 more source

Cholesterols, Apolipoproteins, and Their Associations with the Presence and Severity of Diabetic Retinopathy: A Systematic Review

Vision, 2022
Serum apolipoproteins have been reported as a more significant marker for diabetic retinopathy (DR) compared with serum cholesterols. This article aims to review the associations between serum cholesterols and apolipoproteins, and the presence and ...
Soefiandi Soedarman, King Hans Kurnia, Alberthus Donni Budi Prasetya, Muhammad Bayu Sasongko   +3 more
doaj   +1 more source

Vascular function and cardiovascular risk factors in women with severe flushing [PDF]

, 2011
Background: Seventy per cent of postmenopausal women suffer from hot flushes causing significant morbidity in 25%. Oestrogen replacement provides symptom relief, but its use has declined following safety issues and there is, as yet, no good alternative ...
Andrikoula, Bechlioulis, Brockie, Caballero, Ferrell, Freedman, Freeman, Gambacciani, Ginsburg, Huang, Keating, Khan, Khan, Kronenberg, Kubli, Leal, Lerman, Lobo, Martin, Modena, Morris, Nilsson, Noon, Ramsay, Ramsay, Sattar, The Emerging Risk Factors Collaboration, Thurston, Wardell   +28 more
core   +1 more source