Results 1 to 10 of about 43,955 (304)

A narrative review of impacts of apolipoproteins on atherosclerotic coronary plaques [PDF]

npj Cardiovascular Health
Apolipoproteins are structural components of lipoproteins involved in assembly, enzyme regulation, structural integrity, and receptor binding. Apoprotein(a) forms lipoprotein(a), apolipoprotein A-I drives reverse cholesterol transport, apolipoprotein B ...
Tatsuya Fukase, Tomotaka Dohi
doaj   +2 more sources

Exploring the evolving role of apolipoproteins in oncology: global trends and emerging frontiers [PDF]

Journal of Cancer Research and Clinical Oncology
Background Metabolic reprogramming, especially lipid metabolism, is crucial in cancer progression and treatment resistance. Apolipoproteins are crucial targets for research as they regulate autophagy, oxidative stress, and chemoresistance.
Dianzhe Tian, Zixuan Hu, Zuyi Yang, Lvyuxing Zhao, Haitao Zhao, Xinting Sang, Shunda Du, Yunping Luo, Lei Zhang, Yiyao Xu, Xin Lu   +10 more
doaj   +2 more sources

Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and longitudinal cohort studyResearch in context [PDF]

EBioMedicine
Summary: Background: Apolipoproteins as an integral part of lipoproteins are crucial for the transport and metabolism of lipids. However, there is a lack of longitudinal studies to quantify the concentrations of maternal apolipoproteins from ...
Li Chen, Karen Mei-Ling Tan, Melvin Khee-Shing Leow, Kok Hian Tan, Jerry Kok Yen Chan, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Markus R. Wenk, Sartaj Ahmad Mir   +10 more
doaj   +2 more sources

Apolipoproteins in Psoriasis: The Effect of Acitretin Treatment and UVB Phototherapy [PDF]

Metabolites
Background: Psoriasis is a chronic, multi-system inflammatory disease frequently associated with metabolic syndrome and lipid disturbances. Apolipoproteins, as essential regulators of lipid metabolism, may play a critical role in these metabolic ...
Hanna Myśliwiec, Dorota Kozłowska, Katarzyna Hodun, Bartłomiej Łukaszuk, Agnieszka Owczarczyk-Saczonek, Adrian Chabowski, Iwona Flisiak   +6 more
doaj   +2 more sources

The prognostic significance of HDL-associated apolipoproteins in ascitic fluid from patients with cirrhosis and spontaneous bacterial peritonitis [PDF]

Scientific Reports
Apolipoproteins (Apo) A-I and A-II are major components of high-density lipoproteins (HDL) with immunomodulatory functions. Low serum apoA-I levels indicate complications of cirrhosis. We hypothesized that HDL-associated apolipoproteins in ascitic fluid (
Mohamad Murad, Philipp A. Reuken, Kristin Schubert, Johanna Reißing, Oluwatomi Ibidapo-Obe, Karsten Große, Mick Frissen, Frederic Haedge, Majda El-Hassani, Martin von Bergen, Tony Bruns   +10 more
doaj   +2 more sources

Diagnostic and pathogenetic significance of apolipoprotein disorders in patients with alcoholic fatty liver [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Alcohol is the most common cause of fatty liver. Alcohol metabolism takes place in the liver by alcohol dehydrogenase, to toxic acetaldehyde, with fatty acids accumulation in the liver as a consequence.
Mladenović Bojan, Brzački Vesna, Benedeto-Stojanov Daniela, Mladenović Nikola   +3 more
doaj   +1 more source

Association of apolipoproteins and lipoprotein(a) with metabolic syndrome: a systematic review and meta-analysis

Lipids in Health and Disease, 2023
Background & aims Apolipoproteins and lipoprotein(a) are associated with various cardiometabolic diseases, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, among others.
Juan R. Ulloque-Badaracco, Ali Al-kassab-Córdova, Enrique A. Hernandez-Bustamante, Esteban A. Alarcon-Braga, Miguel Huayta-Cortez, Ximena L. Carballo-Tello, Rosa A. Seminario-Amez, Percy Herrera-Añazco, Vicente A. Benites-Zapata   +8 more
doaj   +1 more source

Apolipoprotein A-I mimetics [PDF]

Current Opinion in Lipidology, 2014
To summarize recent publications in the field of apolipoprotein mimetics.Apolipoprotein mimetic peptides continue to show efficacy in a number of animal models of disease and demonstrate properties that make them attractive as potential therapeutic agents. A number of new apolipoprotein mimetics have been described recently.
Reddy, Srinivasa T, Navab, Mohamad, Anantharamaiah, Gattadahalli M, Fogelman, Alan M   +3 more
openaire   +4 more sources

Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses. [PDF]

PLoS ONE, 2015
Apolipoprotein E (ApoE), an exchangeable apolipoprotein, is necessary for production of infectious Hepatitis C virus (HCV) particles. However, ApoE is not the only liver-expressed apolipoprotein and the role of other apolipoproteins for production of ...
Kathrin Hueging, Romy Weller, Mandy Doepke, Gabrielle Vieyres, Daniel Todt, Benno Wölk, Florian W R Vondran, Robert Geffers, Chris Lauber, Lars Kaderali, François Penin, Thomas Pietschmann   +11 more
doaj   +1 more source

The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat

Journal of Lipid Research, 2022
Lipoprotein(a) [Lp(a)] concentrations are regulated by the LPA gene mainly via the large kringle IV-type 2 (KIV-2) copy number variation and multiple causal variants.
Rebecca Grüneis, Hansi Weissensteiner, Claudia Lamina, Sebastian Schönherr, Lukas Forer, Silvia Di Maio, Gertraud Streiter, Annette Peters, Christian Gieger, Florian Kronenberg, Stefan Coassin   +10 more
doaj   +1 more source