Results 161 to 170 of about 37,488 (288)

Triblock Polyampholyte‐Based Nanovesicles for Targeted Spleen Delivery

Macromolecular Bioscience, EarlyView.
Polymeric nanovesicles, assembled from triblock polyampholytes, exhibit unilamellar structure and enhanced stability through membrane cross‐linking. These nanovesicles demonstrate prolonged blood circulation and selective accumulation in the spleen after intravenous injection in mice, highlighting their potential for targeted drug delivery applications.
Takayoshi Watanabe, Keita Masuda, Pengwen Chen, Horacio Cabral   +3 more
wiley   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Associations Between Lipids and Lipid‐Lowering Drug Target Genes and Osteomyelitis: A Mendelian Randomization Analysis

Medicine Advances, EarlyView.
In this study, we identified several SNPs in PCSK9 as genetic tools to comprehensively assess the influential role of PCSK9 in CHD, CRP, and osteomyelitis. PCSK9 is associated with a lower risk of osteomyelitis, and PCSK9 is also associated with a reduction in CRP concentrations. Our study supports the notion that WC may be a potential mediator between
Zhiyi Zhou, Zhehan Yang, Junpan Chen, Minghao Wen, Jiayuan Lei, Wanzhe Liao, Yahan Li, Linghui Liu, Ziyuan Lu   +8 more
wiley   +1 more source

Enhanced serum-based seed amplification assay for detecting propagative α-synuclein seeds in Parkinson's disease. [PDF]

Transl Neurodegener
Kuang Y, Mao H, Dai W, Gan T, Lin H, Li J, Yang X, Xu P.   +7 more
europepmc   +1 more source

Stealth Drug Delivery of Mouse Serum Albumin‐Coated Paclitaxel‐Loaded Gelatin Nanoparticles for Targeted Cancer Therapy in Mice

Nano Select, EarlyView.
Our study presents a novel approach to localized cancer therapy by developing mouse serum albumin (MSA)‐coated paclitaxel (PTX)‐loaded gelatin nanoparticles (MSA@PTX‐loaded GNPs) as a stealth drug delivery system. Given the challenges of nanoparticle‐based chemotherapy, including rapid opsonization and limited drug accumulation at tumor sites, our work
Md. Annur Sadman, Forhad Bin Faruk, Arifur Rahman Nibir, Tasmihaw Tanha Oishi, Nazifa Siraj Katha, Md. Mujahidul Islam Chowdhury, Rifa Tasfia Faiza, Nishat Tasnim, Saoda Islam Aurni, Tahmina Yasmin, Shazid Md. Sharker   +10 more
wiley   +1 more source

Apolipoproteins in Psoriasis: The Effect of Acitretin Treatment and UVB Phototherapy. [PDF]

Metabolites
Myśliwiec H, Kozłowska D, Hodun K, Łukaszuk B, Owczarczyk-Saczonek A, Chabowski A, Flisiak I.   +6 more
europepmc   +1 more source

Beta cells to brain cells: The pivotal role of insulin and glucose metabolism in Alzheimer's disease

Neuroprotection, EarlyView.
Common metabolic, histochemical, and molecular pathologies: Type 2 diabetes and dementia. Abstract The risk factors and neuropathologies of cognitive decline and the onset and progression of dementia‐related disorders were, until recently, obtuse. A critical predisposing factor to Alzheimer's disease (AD) that has emerged is glucose dysmetabolism.
Stanley S. Schwartz, Elizabeth M. Rhea, William A. Banks, Mary E. Herman   +3 more
wiley   +1 more source

Apolipoprotein and menopausal status are significant influencing factors for diabetic retinopathy in type II diabetes mellitus women. [PDF]

Sci Rep
Pei X, Yao X, Qi D, Yang Y, Fan S, Li Z.
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Impact of a 12-week High-Intensity Interval Training With Spirulina Supplementation on Insulin Resistance-Mediated by Apo-A, -B, and -J in Men With Obesity HIIT With Spirulina on Apolipoproteins. [PDF]

Eur J Sport Sci
Tayebi SM, Bagherian P, Bassami M, Basereh A, Ahmadabadi S.   +4 more
europepmc   +1 more source