Results 221 to 230 of about 25,315 (305)

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Plasma proteomic profiles of patients during oral anti-coagulant treatment with vitamin K antagonists. [PDF]

Br J Haematol
Camilleri E, van Vlijmen BJM, Bos MHA, Wuhrer M, Goodlett DR, Borchers CH, Cannegieter SC, van Rein N, Mohammed Y.   +8 more
europepmc   +1 more source

Apolipoprotein B-100 [PDF]

, 2020
openaire   +1 more source

Human breast milk lipoproteins: A preliminary biochemical characterization

Experimental Physiology, EarlyView.
Abstract Human breast milk (BM) is an essential fluid for infant development, with a dynamic composition adapted to the infant's needs. It contains bioactive lipids like cholesterol, typically transported by lactosomes, extracellular vesicles, and milk fat globules. However, classic cholesterol‐carrying lipoproteins have not been described in BM.
Gabriela Arenas, Andrea Morales, Andrea Leiva, Susana Contreras‐Duarte   +3 more
wiley   +1 more source

The Impact of Polyethylene Glycol Lipid Anchors on the Physicochemical Properties, Protein Corona, Function, and Biodistribution of Lipid Nanoparticles. [PDF]

ACS Nano
Lu CE, Liu K, Gallud A, Meklesh V, Ravnkilde LT, Santos J, Dias Louro F, Miliotis T, Alfonzo-Mendez MA, Rejman J, Panariello L, Barriga HMG, Stevens MM, Höök F, Yanez Arteta M, Ulander J, Jones S, Sabirsh A.   +17 more
europepmc   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

SAA4: An Underdog Within the Serum Amyloid a Superfamily? [PDF]

Int J Mol Sci
Malle E, Madreiter-Sokolowski C, Windpassinger C.   +2 more
europepmc   +1 more source

APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function

The Journal of Physiology, EarlyView.
Abstract figure legend We examined the interaction effect of ovarian hormones and APOE genotype on cerebrovascular and mitochondrial function. Our data revealed that APOEε3 mice that were ovariectomized exhibited impaired endothelial function and greater oxidative stress and inflammation compared to sham controls.
Mackenzie N. Kehmeier, Alexandra Famiano, Abigail E. Cullen, Thomas Leonhardt, Skylyn J. Ferguson, Madeleine Snyder, Carrie E. McCurdy, Daniel J. Tyrrell, Nabil J. Alkayed, Ashley E. Walker   +9 more
wiley   +1 more source

Artificial recombinant high-density protein nanocarriers for precision drug delivery. [PDF]

Chem Sci
Li W, Jia N, Li M, Jiang Y, Lu J.
europepmc   +1 more source

National Trends and Disparities in Cancer Mortality Among Individuals With Alzheimer's Disease and Related Dementias in the United States, 1999–2020

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT As population aging accelerates, the coexistence of cancer and Alzheimer's disease and related dementias (ADRD) is becoming increasingly common. While each condition independently contributes to mortality, national trends in cancer‐related deaths occurring alongside ADRD—and their demographic and geographic disparities—remain poorly defined ...
Aasim Ali, Javed Iqbal, Aimen Anwaar Pannun, Muhammad Talha, Fiza Nisar, Ufaq Reyaz, Muhammad Saad Ansari, Sameen Sarfaraz, Ahmad Butt, Hammad Azam, Muhammad Shamoon, Labeeba Abdul Ghafoor, Armaghana Abdullah, Muhammad Asad Shabbir, Mukesh Kumar Sharma   +14 more
wiley   +1 more source