Results 51 to 60 of about 12,961,080 (334)

Greater enrichment of triacylglycerol-rich lipoproteins with apolipoproteins E and C-III after meals rich in saturated fatty acids than after meals rich in unsaturated fatty acids.

open access: yesAmerican Journal of Clinical Nutrition, 2005
BACKGROUND Although there is considerable interest in the postprandial events involved in the absorption of dietary fats and the subsequent metabolism of diet-derived triacylglycerol-rich lipoproteins, little is known about the effects of meal fatty ...
K. Jackson   +4 more
semanticscholar   +1 more source

Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier   +8 more
wiley   +1 more source

Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.

open access: yesJournal of Lipid Research, 1990
Familial defective apolipoprotein B-100 is a genetic disorder of apolipoprotein B-100 that causes moderate to severe hypercholesterolemia. A single amino acid mutation in apolipoprotein B diminishes the ability of low density lipoproteins to bind to the low density lipoprotein receptor.
Gloria Lena Vega   +9 more
openaire   +4 more sources

Estimation of LDL-Associated Apolipoprotein B from Measurements of Triglycerides and Total Apolipoprotein B [PDF]

open access: yesClinical Chemistry, 2008
Abstract Background: VLDL and chylomicrons may interfere with measurements of apolipoprotein B (apo B) on LDL particles. Ultracentrifugation of samples enriched in chylomicrons and VLDL and subsequent measurement of apo B in the infranate fraction [density (d) = 1.006] removes this interference. This apo B fraction is called “LDL–apo B.”
G. Russell Warnick, Arthur M. Baca
openaire   +3 more sources

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar   +6 more
wiley   +1 more source

Radioimmunotherapy‐induced intratumoral changes in cervical squamous cell carcinoma at single‐cell resolution

open access: yes, 2022
Cancer Communications, Volume 42, Issue 12, Page 1407-1411, December 2022.
Chao Liu   +9 more
wiley   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

Evaluation of ABCA1 gene polymorphism as a prognostic index of fibrosis progression in NAFLD patients

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
Dyslipidemias, hepatic steatosis index, and ABCA1 (rs1800977) gene polymorphism CC genotype; were the only independent predictors of advanced fibrosis in NAFLD‐patients. Abstract Introduction It had been evident that non‐alcoholic fatty liver disease (NAFLD) is the new era epidemic.
Samar E. Ghanem   +7 more
wiley   +1 more source

Dynamic interfacial properties of human apolipoproteins A-IV and B-17 at the air/water and oil/water interface

open access: yesJournal of Lipid Research, 2000
Viscoelastic behavior of proteins at interfaces is a critical determinant of their ability to stabilize emulsions. We therefore used air bubble surfactometry and drop volume tensiometry to examine the dynamic interfacial properties of two plasma ...
Richard B. Weinberg   +3 more
doaj  

Both Serum Apolipoprotein B and the Apolipoprotein B/Apolipoprotein A-I Ratio Are Associated with Carotid Intima-Media Thickness

open access: yesPLoS ONE, 2013
Previous studies indicated that apolipoprotein measurements predicted cardiovascular disease (CVD) risk; however, associations between apolipoproteins and carotid intima-media thickness (CIMT) were less explored.The cross-sectional study included 6069 participants aged 40 years or older with NGT from Shanghai, China.
Zhi Yang   +11 more
openaire   +5 more sources

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