Results 71 to 80 of about 12,961,080 (334)

Affinity‐Based Isolation and One‐Pot Analysis of Extracellular Vesicles from Biofluids Using Phase Separated Zwitterionic Coacervates

open access: yesAdvanced Science, EarlyView.
This study presents a novel method for affinity‐based isolation and analysis of extracellular vesicles from biofluids using phase‐separated zwitterionic coacervates functionalized with a membrane‐sensing peptide. This technology minimizes nonspecific binding, enabling high‐yield isolation and direct one‐pot biomarker profiling.
Francesca Torrini   +8 more
wiley   +1 more source

Stilbene‐based derivatives as potential inhibitors of trimethylamine (TMA)‐lyase affect gut microbiota in coronary heart disease

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 93-100, January 2023., 2023
Docking results showed Resveratroloside had the highest Vina score, indicating that it was the most active and might be employed as a lead molecule for further structural modification. The possible action process of TMA‐Lyase lead compound was described, which further affects the occurrence and development of CHD.
Jincai Li   +3 more
wiley   +1 more source

Serum lipids, lipoproteins and apolipoproteins A and B in epileptic patients treated with valproic acid, carbamazepine or phenobarbital

open access: yesActa Neurologica Scandinavica, 1991
Serum lipids, lipoproteins and apolipoproteins A and B were measured in 101 epileptic patients receiving chronic treatment with valproic acid, carbamazepine or phenobarbital and in 75 age‐ and sex‐matched control subjects.
E. P. Calandre   +3 more
semanticscholar   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang   +18 more
wiley   +1 more source

Tongxinluo enhances the effect of atorvastatin on the treatment of atherosclerosis with chronic obstructive pulmonary disease by maintaining the pulmonary microvascular barrier

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 390-407, January 2023., 2023
COPD aggravates AS, possibly through the destruction of pulmonary microvascular barrier function; thus, lung inflammation triggers systemic inflammation. In treating COPD with AS, TXL enhances the antiatherosclerotic effect of Ato, protecting the pulmonary microvascular barrier.
Xiangnan Kuang   +11 more
wiley   +1 more source

Lipid and apolipoprotein concentrations in prenodal leg lymph of fasted humans: associations with plasma concentrations in normal subjects, lipoprotein lipase deficiency, and LCAT deficiency

open access: yesJournal of Lipid Research, 2000
The extent to which lipid and apolipoprotein (apo) concentrations in tissue fluids are determined by those in plasma in normal humans is not known, as all studies to date have been performed on small numbers of subjects, often with dyslipidemia or ...
M.N. Nanjee   +3 more
doaj  

A proteomic study of the apolipoproteins in LDL subclasses in patients with the metabolic syndrome and type 2 diabetes Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M500161-JLR200

open access: yesJournal of Lipid Research, 2005
The exchangeable apolipoproteins present in small, dense LDL (sdLDL) and large, buoyant LDL subclasses were evaluated with a quantitative proteomic approach in patients with the metabolic syndrome and with type 2 diabetes, both with subclinical ...
P. Davidsson   +6 more
semanticscholar   +1 more source

Engineering the Immune Response to Biomaterials

open access: yesAdvanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam   +12 more
wiley   +1 more source

Retinal regions shape human and murine Müller cell proteome profile and functionality

open access: yesGlia, Volume 71, Issue 2, Page 391-414, February 2023., 2023
Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan   +15 more
wiley   +1 more source

African American-white differences in lipids, lipoproteins, and apolipoproteins, by educational attainment, among middle-aged adults: the Atherosclerosis Risk in Communities Study.

open access: yesAmerican Journal of Epidemiology, 1998
Measures of socioeconomic status have been shown to be related positively to levels of high density lipoprotein (HDL) cholesterol in white men and women and negatively in African American men.
P. Metcalf   +8 more
semanticscholar   +1 more source

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