Results 161 to 170 of about 18,813,566 (369)

Human apolipoprotein E mRNA. cDNA cloning and nucleotide sequencing of a new variant.

, 1984
J W McLean, Nabil A. Elshourbagy, David J. Chang, Robert W. Mahley, John M. Taylor   +4 more
openalex   +1 more source

HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background The ratio of high‐density lipoprotein cholesterol (HDL‐C) to low‐density lipoprotein cholesterol (LDL‐C) predicts cardiovascular disease (CVD) endpoints, yet its prognostic validity in high‐risk populations and for type 2 diabetes mellitus (T2DM)‐related adverse events remains unestablished. Methods This study included 32,609 people
Biting Lin, Yunzhi Ling, Gengyu Zhou, Ziqing Ruan, Fan Chen, Simiao Chen, Tingting Weng, Yuanfan Zhu, Jingyi Lin, Ling Yu, Kaiyang Lin   +10 more
wiley   +1 more source

Protein deglycosylation can drastically affect the cellular uptake [PDF]

, 2019
Ghazaryan, A., Landfester, K., Mailänder, V.   +2 more
core   +2 more sources

Variation in Neurodegeneration‐Linked Brain Regions in Young Adult APOE E4 Carriers With Spina Bifida

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Possible pleiotropic effects of apolipoprotein E4 (APOE E4) in individuals with congenital brain malformations are relatively unknown. Our goal was to determine if neurodegeneration‐linked brain region volumes differ significantly between E4 carriers and noncarriers in young adults with spina bifida (SB). Methods Eleven individuals ( 
Joan M. Jasien, Jacques A. Stout, Mohamad A. Mikati, Robert J. Anderson, Brittany G. Nave, Herbert E. Fuchs, Brian Smith, Alexandra Badea, Jeffrey N. Browndyke   +8 more
wiley   +1 more source

Analysis of high density lipoprotein apolipoproteins by capillary zone and capillary SDS gel electrophoresis

Journal of Lipid Research, 1998
We describe new methods for analyzing the apolipoproteins (apo) of the high density lipoproteins (HDL) of several species by two modes of capillary electrophoresis: size separation using a molecular sieving buffer, and capillary zone electrophoresis (CZE)
Joseph Stocks, M. Nazeem Nanjee, Norman E. Miller   +2 more
doaj  

The association of hepatitis C virus glycoproteins with apolipoproteins E and B early in assembly is conserved in lipoviral particles. [PDF]

J Biol Chem, 2014
Boyer A, Dumans A, Beaumont E, Etienne L, Roingeard P, Meunier JC.   +5 more
europepmc   +1 more source

Regulation of serum apolipoprotein E metabolism: role of chylomicron metabolism.

, 1982
J G DeLamatre, Brian R. Krause, Paul S. Roheim   +2 more
openalex   +1 more source

A rapid, semiautomated method for apolipoprotein E genotyping. [PDF]

, 1993
Chunxue Guo, Peter Marynen, J.-J. Cassiman   +2 more
openalex   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source

Protein heterogeneity of lipoprotein particles containing apolipoprotein A-I without apolipoprotein A-II and apolipoprotein A-I with apolipoprotein A-II isolated from human plasma.

Journal of Lipid Research, 1988
The protein heterogeneity of fractions isolated by immunoaffinity chromatography on anti-apolipoprotein A-I and anti-apolipoprotein A-II affinity columns was analyzed by high resolution two-dimensional gel electrophoresis.
R W James, D Hochstrasser, J D Tissot, M Funk, R Appel, F Barja, C Pellegrini, A F Muller, D Pometta   +8 more
doaj