Influence of apolipoprotein-E gene on lipid profile, physical activity and body fat relationship
Revista Brasileira de Cineantropometria e Desempenho Humano, 2012 Physical activity and body fat modify lipemia, and this effect seems to be influenced by apolipoprotein-E (APOE) gene polymorphism. Thus, the purpose of this article was to review main results of studies that have analyzed the relation of APOE gene with ...
Thales Boaventura Rachid Nascimento +2 more
doaj +1 more source
Biomedical Papers, 2015 Aims: We sought to identify biochemical predictors that indicate susceptibility to in-stent restenosis (ISR) after coronary artery bare-metal stenting.
Leos Pleva +7 more
doaj +1 more source
Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation. [PDF]
, 2012 ObjectivePostprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury.
Altman, Robin +10 more
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Production of human recombinant proapolipoprotein A-I in Escherichia coli: purification and biochemical characterization [PDF]
, 1989 A human liver cDNA library was used to isolate a clone coding for apolipoprotein A-I (Apo A-I). The clone carries the sequence for the prepeptide (18 amino acids), the propeptide (6 amino acids), and the mature protein (243 amino acids).
Bollen, A. +12 more
core +1 more source
Endothelial Cell-specific Loss of Breast Cancer Susceptibility Gene 2 Exacerbates Atherosclerosis [PDF]
arXiv, 2023 The BReast CAncer type 2 susceptibility protein (BRCA2) responds to DNA damage by participating in homology-directed repair. BRCA2 deficiency culminates in defective DNA damage repair (DDR) that when prolonged leads to the accumulation of DNA damage causing cancer or apoptosis.
arxiv
The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]
, 1981 Peer ...
Giesemann, G. +4 more
core +2 more sources
Apolipoprotein E Isoforms and AMD [PDF]
, 2015 The cholesterol transporting protein apolipoprotein E (ApoE) occurs in three allelic variants in humans unlike in other species. The resulting protein isoforms E2, E3 and E4 exhibit differences in lipid binding, integrating into lipoprotein particles and affinity for lipoprotein receptors. ApoE isoforms confer genetic risk for several diseases of aging
Toops, Kimberly A +2 more
openaire +5 more sources
Effect of Amyloid Beta on Cholesterol Metabolism-Correlated microRNAs in Primary Cultured Astrocytes of C57BL/6J Mice: A Focus on CYP46A1 and APOE Genes [PDF]
Cell JournalObjective: The accumulation of amyloid plaques and disturbance of cholesterol homeostasis are implicated in thepathophysiology of Alzheimer’s disease. Apolipoprotein E (ApoE) and cholesterol 24-hydroxylase (CYP46A1) are keyproteins involved in the efflux
Bahar Jaberian Asl +6 more
doaj +1 more source
LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit [PDF]
, 2011 Apolipoprotein A-I and Apolipoprotein E promote different steps of reverse cholesterol transport, including lecithin-cholesterol acyltransferase stimulation.
A. Carlucci +6 more
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Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. [PDF]
, 2006 Cell entry of hepatitis C virus, pseudoparticles (HCVpp) and cell culture grown virus (HCVcc), requires the interaction of viral glycoproteins with CD81 and other as yet unknown cellular factors.
Boullier, Agnès +6 more
core +1 more source