Isquemia e reperfusão de músculo sóleo de ratos sob ação da pentoxifilina Ischemia and reperfusion of the soleus muscle of rats with pentoxifylline [PDF]
CONTEXTO: A reperfusão de músculo esquelético piora as lesões já presentes no período de isquemia, pois a produção de espécies reativas de oxigênio, associadas à intensa participação de neutrófilos, amplia a reação inflamatória que induz alterações ...
José Lacerda Brasileiro+7 more
doaj +3 more sources
Effects of Panax ginseng, Turnera diffusa and Heteropterys tomentosa extracts on hippocampal apoptosis of aged rats [PDF]
OBJECTIVE: To verify if the medicinal plants Panax ginseng C.A. Mey, Turnera diffusa Willd. ex Schult., and Heteropterys tomentosa O. Mach., which are amply used by the population as tonics and cognition enhancers, could have a protective effect on cell ...
Andréia Gomes Bezerra+3 more
doaj +2 more sources
Expressão de marcadores de proliferação celular e apoptose em carcinoma basocelular [PDF]
FUNDAMENTOS: O carcinoma basocelular é o câncer mais comum em humanos. Estudos que utilizam recursos da biologia molecular e genética, associados à histomorfologia, permitem a identificação de fatores de risco no desenvolvimento de lesões mais ...
Marília de Pádua Dornelas Corrêa+4 more
openalex +7 more sources
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
The acknowledgment that pollutants might influence the epigenome raises serious concerns regarding their long-term impact on the development of chronic diseases. The herbicide glyphosate has been scrutinized for an impact on cancer incidence, but reports
Manon Duforestel+32 more
doaj +1 more source
Relationship of PSC to embryos: Extending and refining capture of PSC lines from mammalian embryos. [PDF]
ESCs were first derived from mouse diapause blastocysts or isolated ICMs plated onto fibroblast feeders in a medium containing FBS. Feeders were then replaced with LIF, and later, BMP4 was substituted for serum. GSK3 and ERK inhibition finally enabled efficient derivation of ESCs from embryos of all strains of mice and rats.
Ying QL, Nichols J.
europepmc +2 more sources
Apoptosis and necrosis of blood and milk polymorphonuclear leukocytes in early and midlactating healthy cows. [PDF]
Increased milk somatic cell counts (SCC) are used as an indicator for bovine mastitis. During mastitis, polymorphonuclear leukocytes (PMN) become the predominant cell type.
Burvenich, Christian+3 more
core +4 more sources
Die Rolle von p53 und der Proteinphosphatase 2C in der neuronalen Apoptose [PDF]
Störungen der neuronalen Apoptose sind an einer ganzen Reihe von Krankheitsbildern beteiligt, darunter so häufige wie Krebs, neurodegenerative Erkrankungen und Schlaganfall.
Krieglstein, Josef (Prof. Dr. Dr.)+1 more
core +1 more source
EFEITO DA RAPAMICINA SOBRE A APOPTOSE EM CULTURA DE LINFÓCITOS HUMANOS PERIFÉRICOS
Objetivo: avaliar a indução de apoptose pela rapamicina em linfócitos humanos periféricos. Métodos: Polimorfos mononucleares foram separados do sangue periférico de voluntários sadios através de centrifugação em gradiente de densidade.
Taísa Aozani Prochnow+4 more
doaj +1 more source
The effect of an HIV-1 viral protease inhibitor on staurosporine-induced apoptosis in immortalized mesangial cells [PDF]
CONTEXT: Progressive glomerular sclerosis is a condition characterized by the accumulation of glomerular extracellular matrix and a decrease in the number of glomerular cells.
Camargo, Simone Mafalda Rodrigues+2 more
core +4 more sources