Troxerutin Reduces Kidney Damage against BDE‐47‐Induced Apoptosis via Inhibiting NOX2 Activity and Increasing Nrf2 Activity [PDF]
Qun Shan +6 more
openalex +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Endoplasmic reticulum stress-mediated programmed cell death in the tumor microenvironment. [PDF]
Chai H, Hu Q, Yao S, Ma S, Su W.
europepmc +1 more source
Abstract Objective This study aimed to investigate the comorbid mechanisms linking type 2 diabetes mellitus (T2DM) and vascular dementia (VaD), focusing on the roles of astrocytes and neurons, and to identify potential therapeutic traditional Chinese medicines (TCMs) and compounds.
Meiyue Li +5 more
wiley +1 more source
Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications. [PDF]
Gonciarz M +4 more
europepmc +1 more source
Histone Deacetylase Inhibitors Dose-Dependently Switch Neutrophil Death from NETosis to Apoptosis [PDF]
Hussein J. Hamam, Nades Palaniyar
openalex +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
Antonio Carlesso +4 more
doaj +1 more source
Genotype-Dependent Modulation of Macrophage Apoptosis and T Lymphocyte Responses by Duck Tembusu Virus Potentially Contributes to Genotype-Specific Immunopathogenesis. [PDF]
Nedumpun T +3 more
europepmc +1 more source

