Results 101 to 110 of about 1,812,730 (293)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
International Competition Policy Advisory Committee: Antitrust Division
, 1998 The International Competition Policy Advisory Committee (ICPAC) was formed in November 1997 to address the global antitrust problems of the 21st ...
DOJ/ATR International Competition Policy Advisory Committee
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Exploring the ordoliberal paradigm : the competition-democracy nexus [PDF]
, 2016 The present article purports to shed a new light on ordoliberalism and to explore its role in EU competition law. For this purpose, the article analyses the ordoliberal school of thought in its historical context and re-conceptualizes its understanding ...
DEUTSCHER, Elias, MAKRIS, Stavros
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2003 Interactions between two species that result in reduced growth rates for both and extinction of one of the species are generally considered cases of asymmetric interspecific competition.
Giovanelli Alexandre +2 more
doaj
Tri-trophic interactions among Fopius arisanus, Tephritid species and host plants suggest apparent competition. [PDF]
Ecol Evol, 2023 Moquet L +3 more
europepmc +1 more source
Resource competition and apparent competition in declining mule deer (Odocoileus hemionus)
, 2017 Resource competition and apparent competition have both been suggested as the cause of mule deer (Odocoileus hemionus (Rafinesque, 1817)) decline concurrent with white-tailed deer (Odocoileus virginianus (Zimmerman, 1780)) increase.
Robert B. Wielgus
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
EcosphereHost species heterogeneity can drive parasite dynamics through variation in host competency as well as host abundance. We explored how elk (Cervus canadensis) with apparent subclinical infestations of winter tick (Dermacentor albipictus) may be a cryptic
Troy Koser +11 more
doaj +1 more source