Results 101 to 110 of about 2,123,628 (287)

Gibbs Sampling for (Coupled) Infinite Mixture Models in the Stick Breaking Representation

, 2012
Nonparametric Bayesian approaches to clustering, information retrieval, language modeling and object recognition have recently shown great promise as a new paradigm for unsupervised data analysis.
Ihler, Alexander T., Porteous, Ian, Smyth, Padhraic, Welling, Max   +3 more
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Compression deformation behaviors of sheet metals at various clearances and side forces

MATEC Web of Conferences, 2015
Modeling sheet metal forming operations requires understanding of plastic behaviors of sheet metals along non-proportional strain paths. The plastic behavior under reversed uniaxial loading is of particular interest because of its simplicity of ...
Zhan Mei, Wang Xianxian, Cao Jian, Yang He   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Reliability analysis of mine ventilation fans based on Markov process theory

Горные науки и технологии
The reliability of mine ventilation fans plays a crucial role in aerological systems and is determined by a combination of various geological, mining-technological, and structural factors, most of which are stochastic in nature.
P. V. Vyatkin, N. G. Valiev, D. I. Simisinov, E. B. Volkov   +3 more
doaj   +1 more source

Implementing Loss Distribution Approach for Operational Risk

, 2009
To quantify the operational risk capital charge under the current regulatory framework for banking supervision, referred to as Basel II, many banks adopt the Loss Distribution Approach.
Artzner, Aue, Basel Committee on Banking Supervision, Bedard, Berger, Böcker, Böcker, Böcker, Böcker, Bühlmann, Bühlmann, Chavez-Demoulin, Chernobai, Chernobai, Cont, Cruz, Dalla Valle, Degen, Efron, Embrechts, Embrechts, Embrechts, Embrechts, Embrechts, Ergashev, Frachot, Gerhold, Giacometti, Gilks, Gustafsson, Hess, Joe, Johnson, King, Klugman, Lambrigger, Lehmann, Lindskog, Luo, Luo, Marshall, McNeil, Mignola, Mignola, Nelson, Nešlehová, Panjer, Peters, Peters, Peters, Peters, Powojowski, Press, Robert, Sandström, Schaller, Shevchenko, Shevchenko, Shevchenko, Sundt, Wüthrich   +60 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequential Monte Carlo Squared for online inference in stochastic epidemic models

Epidemics
Effective epidemic modeling and surveillance require computationally efficient methods that can continuously update parameter estimates as new data becomes available.
Dhorasso Temfack, Jason Wyse
doaj   +1 more source

FORMALIZATION OF THE VIRTUAL EVALUATION OF STRAIN INTENSITY IN SPDed COMMERCIALLY PURE COPPER BILLET

Acta Metallurgica Slovaca, 2014
This work presented the results of solution of the strain intensity evolution in a commercially pure copper billet in the process of severe plastic deformation (SPD) by equal channel angular pressing (ECAP) technique.
Song-Jeng Huan, Vladimir Ivanovich Semenov, Elvira Ildarovna Fakhretdinova, Arseniy Georgievich Raab   +3 more
doaj   +1 more source