Results 71 to 80 of about 2,123,628 (287)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Bayesian semiparametric inference for multivariate doubly-interval-censored data [PDF]

open access: yes, 2010
Based on a data set obtained in a dental longitudinal study, conducted in Flanders (Belgium), the joint time to caries distribution of permanent first molars was modeled as a function of covariates.
De Iorio, Maria   +3 more
core   +4 more sources

Gating properties of the P2X2a and P2X2b receptor channels: Experiments and mathematical modeling

open access: yesThe Journal of General Physiology, 2012
Adenosine triphosphate (ATP)-gated P2X2 receptors exhibit two opposite activation-dependent changes, pore dilation and pore closing (desensitization), through a process that is incompletely understood.
A. Khadra   +5 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Early aspects: aspect-oriented requirements engineering and architecture design [PDF]

open access: yes, 2004
This paper reports on the third Early Aspects: Aspect-Oriented Requirements Engineering and Architecture Design Workshop, which has been held in Lancaster, UK, on March 21, 2004.
Araújo, João   +3 more
core   +4 more sources

Stereolithography Cure Process Modeling Using Acrylate Resin [PDF]

open access: yes, 2004
In this paper, a complex stereolithography (SL) cure process model is presented that incorporates transient thermal and chemical effects which influence final part shape and properties.
Henderson, Clifford L.   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

An Analytical Formula for the Transition Density of a Conic Combination of Independent Squared Bessel Processes with Time-Dependent Dimensions and Financial Applications

open access: yesMathematics
The squared Bessel process plays a central role in stochastic analysis, with broad applications in mathematical finance, physics, and probability theory.
Nopporn Thamrongrat   +3 more
doaj   +1 more source

Felt Accountability and Managerial Performance: The Moderation Effects of Organizational Commitment and Work Motivation (Empirical Study on Medical Managers of Community Health Centers in Pemalang Regency) [PDF]

open access: yesSHS Web of Conferences
This research aims to scrutinize the effect of felt accountability on managerial performance with organizational commitment and work motivation as moderating variables.
Munasifa Naelal, Pratolo Suryo
doaj   +1 more source

A comprehensive study on battery electric modeling approaches based on machine learning

open access: yesEnergy Informatics, 2021
Battery electric modeling is a central aspect to improve the battery development process as well as to monitor battery system behavior. Besides conventional physical models, machine learning methods show great potential to learn this task using in ...
Felix Heinrich   +2 more
doaj   +1 more source

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