Results 61 to 70 of about 223,993 (286)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

An Approximate Transfer Function Model for a Double-Pipe Counter-Flow Heat Exchanger

open access: yesEnergies, 2021
The transfer functions G(s) for different types of heat exchangers obtained from their partial differential equations usually contain some irrational components which reflect quite well their spatio-temporal dynamic properties. However, such a relatively
Krzysztof Bartecki
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A priori bounds for truncation error of branched continued fraction expansions of Horn's hypergeometric functions $H_4$ and their ratios

open access: yesResearches in Mathematics
The paper considers the extension of analytic functions by a special family of functions — branched continued fractions. The truncation error bounds for branched continue fraction expansions of the Horn's hypergeometric functions $H_4$ and their ratios ...
R.I. Dmytryshyn   +3 more
doaj   +1 more source

Colebrook’s Flow Friction Explicit Approximations Based on Fixed-Point Iterative Cycles and Symbolic Regression

open access: yesComputation, 2019
The logarithmic Colebrook flow friction equation is implicitly given in respect to an unknown flow friction factor. Traditionally, an explicit approximation of the Colebrook equation requires evaluation of computationally demanding transcendental ...
Dejan Brkić, Pavel Praks
doaj   +1 more source

A class of algorithms for rational approximation of functions formally defined by power series [PDF]

open access: yes, 1972
Corresponding sequence algorithms are defined and shown to exist for a wide range of corresponding continued fractions. Particular examples of these algorithms are given, including an algorithm for forming Pade approximants, and an error analysis is ...
Murphy, J A, O'donohoe, M R
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

On the analytical continuation of the ratio $H_4(\alpha,\delta+1;\gamma,\delta;-\mathbf{z})/H_4(\alpha,\delta+2;\gamma,\delta+1;-\mathbf{z})$

open access: yesResearches in Mathematics
The paper considers the problem of analytical continuation of special functions by branched continued fractions. These representations play an important role in approximating of special functions that arise in various applied problems. By improving the
R. Dmytryshyn, C. Cesarano, I.-A. Lutsiv
doaj   +1 more source

On Lp-approximation by Mütz rational functions(Müntz有理函数的加权Lp逼近)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2017
考察了加Jacobi权w(x)=xα(1-x)α(α≥0)的Lp空间中Müntz有理函数的逼近问题.利用K-泛函与加权光滑模的等价性给出了逼近阶的估计以及Ditzian-Totik型定理.所得结果将已有文献中的相应结论推广到了加权情形.
WANGJunxia(王军霞)   +1 more
doaj   +1 more source

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