Results 81 to 90 of about 57,073,214 (327)

Approximation by quotients of rational inner functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1979
Let u be a continuous unimodular function on the n -dimensional torus T
openaire   +2 more sources

On Best Approximation By Rational And Holomorphic Mappings Between Banach Spaces

open access: yes, 2015
After proving a generalized version of Garkavi's theorem, we give as applications proofs of existence results on best approximation by polynomials, and fractional linear and holomorphic operators between Banach spaces.
Roversi M.S.M.   +5 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Floor, ceiling and the space between

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science
Motivated by a question on the ranges of the commutators of dilated floor functions in [10], together with a related problem in [3], we investigate the precise ranges of certain generalized polynomials dependent on a real parameter. Our analysis requires
Bényi Árpád, Ćurgus Branko
doaj   +1 more source

Padé approximants and noise: rational functions

open access: yesJournal of Computational and Applied Mathematics, 1999
Diagonal Padé approximants of a rational function, which has been perturbed by random noise, are considered. Some nice pictures illustrate how the zeros and poles of the approximants are located.
Gilewicz, Jacek, Pindor, Maciej
openaire   +1 more source

Approximation by rational functions in hardy space [PDF]

open access: yes, 2000
The denseness of rational functions with prescribed poles in the Hardy space and disk algebra is ...
Xin, L. I., Li, Xin
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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