Results 81 to 90 of about 11,753 (303)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Uniform approximation with rational functions having negative poles
, 1978 A general theory of uniform approximation with rational functions having negative poles is developed. An existence theory is given and local characterization and uniqueness results are developed.
Taylor, G.D, Kaufman, E.H
core +1 more source
Prefractal as the source of new rational approximations of functions with a fractal representation
Наука. Инновации. Технологии, 2022 The Article is devoted to the problem of accelerating the convergence of polynomial and rational approximations of functions. In the theory of approximation of functions often used the idea of reducing the interval change in the argument as a method to ...
Petr Kirillovich Korneev +4 more
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Rational and generalised rational Chebyshev approximation problems and their applications
, 2022 In this research, we study rational and generalised rational Chebyshev approximation problems, their extensions, and their applications in different disciplines.
Vinesha Peiris (10975920)
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Stability of best rational Chebyshev approximation
, 1990 In this paper we consider best Chebyshev approximation to continuous functions by generalized rational functions using an optimization theoretical approach introduced in [B. Brosowski and C.
Brosowski, Bruno, Guerreiro, Claudia
core +1 more source
Rahman’s Biorthogonal Rational Functions and Superconformal Indices [PDF]
, 2017 We study biorthogonal functions related to basic hypergeometric integrals with coupled continuous and discrete components. Such integrals appear as superconformal indices for three-dimensional quantum field theories and also in the context of solvable ...
Hjalmar Rosengren +2 more
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source