Results 51 to 60 of about 10,186 (263)

Colebrook’s Flow Friction Explicit Approximations Based on Fixed-Point Iterative Cycles and Symbolic Regression

open access: yesComputation, 2019
The logarithmic Colebrook flow friction equation is implicitly given in respect to an unknown flow friction factor. Traditionally, an explicit approximation of the Colebrook equation requires evaluation of computationally demanding transcendental ...
Dejan Brkić, Pavel Praks
doaj   +1 more source

Approximating Threshold Circuits by Rational Functions

open access: yesInformation and Computation, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ramamohan Paturi, Michael E. Saks
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

On the Distribution of Zeros and Poles of Rational Approximants on Intervals

open access: yesAbstract and Applied Analysis, 2012
The distribution of zeros and poles of best rational approximants is well understood for the functions 𝑓(𝑥)=|𝑥|𝛼, 𝛼>0. If 𝑓∈𝐶[−1,1] is not holomorphic on [−1,1], the distribution of the zeros of best rational approximants is governed by the equilibrium ...
V. V. Andrievskii   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Prefractal as the source of new rational approximations of functions with a fractal representation

open access: yesНаука. Инновации. Технологии, 2022
The Article is devoted to the problem of accelerating the convergence of polynomial and rational approximations of functions. In the theory of approximation of functions often used the idea of reducing the interval change in the argument as a method to ...
Petr Kirillovich Korneev   +4 more
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Padé approximants and noise: rational functions

open access: yesJournal of Computational and Applied Mathematics, 1999
Diagonal Padé approximants of a rational function, which has been perturbed by random noise, are considered. Some nice pictures illustrate how the zeros and poles of the approximants are located.
Gilewicz, Jacek, Pindor, Maciej
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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