Results 71 to 80 of about 223,993 (286)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

On the Distribution of Zeros and Poles of Rational Approximants on Intervals

Abstract and Applied Analysis, 2012
The distribution of zeros and poles of best rational approximants is well understood for the functions 𝑓(𝑥)=|𝑥|𝛼, 𝛼>0. If 𝑓∈𝐶[−1,1] is not holomorphic on [−1,1], the distribution of the zeros of best rational approximants is governed by the equilibrium ...
V. V. Andrievskii, H.-P. Blatt, R. K. Kovacheva   +2 more
doaj   +1 more source

Intrinsic approximation for fractals defined by rational iterated function systems - Mahler's research suggestion

, 2014
Following K. Mahler's suggestion for further research on intrinsic approximation on the Cantor ternary set, we obtain a Dirichlet type theorem for the limit sets of rational iterated function systems.
Broderick, Bugeaud, David Simmons, Fishman, Hutchinson, Kleinbock, Kleinbock, Kristensen, Levesley, Lior Fishman, Mahler, Mattila, Ramanujan, Schmidt, Weiss   +14 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Prefractal as the source of new rational approximations of functions with a fractal representation

Наука. Инновации. Технологии, 2022
The Article is devoted to the problem of accelerating the convergence of polynomial and rational approximations of functions. In the theory of approximation of functions often used the idea of reducing the interval change in the argument as a method to ...
Petr Kirillovich Korneev, Irina Alexandrovna Zhuravleva, Elena Vladimirovna Nepretimova, Andrey Vladimirovich Gladkov, Alexei Mikhailovich Lyagin   +4 more
doaj  

Almost reducibility for finitely differentiable SL(2,R)-valued quasi-periodic cocycles

, 2011
Quasi-periodic cocycles with a diophantine frequency and with values in SL(2,R) are shown to be almost reducible as long as they are close enough to a constant, in the topology of k times differentiable functions, with k great enough. Almost reducibility
Chavaudret C, Claire Chavaudret, Eliasson L H, Fayad B, Hadj Amor S, Zehnder E   +5 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Discrete Least-norm Approximation by Nonnegative (Trigonomtric) Polynomials and Rational Functions [PDF]

Polynomials, trigonometric polynomials, and rational functions are widely used for the discrete approximation of functions or simulation models.Often, it is known beforehand, that the underlying unknown function has certain properties, e.g.
Hertog, D. den, Klerk, E. de, Siem, A.Y.D.   +2 more
core   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source