HGF modulates actin cytoskeleton remodeling and contraction in testicular myoid cells [PDF]
, 2015 The presence of the HGF/Met system in the testicular myoid cells was first discovered by our group. However, the physiological role of this pathway remains poorly understood. We previously reported that HGF increases uPA secretion and TGF-β activation in
Angela, Catizone +6 more
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The novel serine protease PreR-Co promotes endothelium-independent vasorelaxation in rabbit aortic rings [PDF]
, 2003 The effect of a novel enzyme (PreR-Co) that activates renal prorenin was studied on rabbit aortas with and without endothelium. It was tested 1) in the basal tone of nonstimulated or ANG II-sensitized rings or rings precontracted with norepinephrine (NE),
Coviello, Alfredo +5 more
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Influence of ultra-low dose Aprotinin on thoracic surgical operations: a prospective randomized trial [PDF]
, 2008 Background The blood saving effect of aprotinin has been well documented in cardiac surgery. In thoracic surgery, very few recent studies, using rather high doses of aprotinin, have shown a similar result.
A Sedrakyan +27 more
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Aprotinin Attenuates the Elevation of Pulmonary Vascular Resistance After Cardiopulmonary Bypass [PDF]
, 2006 Pulmonary vascular resistance (PVR) is generally believed to be elevated after cardiopulmonary bypass (CPB) due to whole body inflammation. Aprotinin has an anti-inflammatory action, and it was hypothesized that aprotinin would attenuate the PVR increase
Ali +36 more
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Binding of sodium dodecyl sulfate to aprotinin and its effect on the aprotinin molecule.
Chemical and Pharmaceutical Bulletin, 1986 When the basic protease inhibitor aprotinin was treated with sodium dodecyl sulfate (SDS), it showed an increased apparent molecular weight upon SDS gel electrophoresis. The amount of SDS bound to aprotinin was much lower than that bound to aprotinin treated with SDS and mercaptoethanol (ME).
openaire +4 more sources
The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines [PDF]
, 2011 Supplementary to the efficient inhibition of trypsin, chymotrypsin, plasma kallikrein, and plasmin already described by the EcTI inhibitor from Enterolobium contortisiliquum, it also blocks human neutrophil elastase (K(iapp)=4.3 nM) and prevents phorbol ...
Bhoola K.D. +16 more
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In Nordic countries 30-day mortality rate is half that estimated with EuroSCORE II in high-risk adult patients given aprotinin and undergoing mainly complex cardiac procedures [PDF]
Objectives: To describe current on- (isolated coronary arterty bypass grafting, iCABG) and off-label (non-iCABG) use of aprotinin and associated safety endpoints in adult patients undergoing high-risk cardiac surgery in Nordic countries.
Cunha-Goncalves, Doris +10 more
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Pilotstudie zur intraoperativen Aprotinin-Applikation bei Patienten mit Rektumtumoren und ihre Auswirkung auf Transfusionsbedarf und Blutverlust [PDF]
, 2002 Im Rahmen dieser Arbeit wurde eine randomisierte, plazebokontrollierte Doppelblindstudie durchgeführt, in der Patienten mit Rektumkarzinom intraoperativ den Serinprotinasen-Inhibitor Aprotinin erhielten. Hauptziel dieser Studie war es, durch die Gabe von
Heckl, Ute
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