Results 71 to 80 of about 114,758 (340)

Randomized study of aprotinin and DDAVP to reduce postoperative bleeding after cardiopulmonary bypass surgery [PDF]

, 1994
BACKGROUND: Patients on cardiopulmonary bypass (CPB) have an increased susceptibility to postoperative bleeding. Previous reports using desmopressin acetate (DDAVP) for the prevention of postoperative bleeding have given contradictory results, whereas ...
Arroyo, J.L. (José L.), Hidalgo, F. (Francisco), Llorens, R. (Rafael), Melero, J.M. (José María), Paramo, J.A. (José Antonio), Rocha, E. (Eduardo)   +5 more
core   +1 more source

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

Advanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang, Juzheng Yuan, Niu Dai, Yanlin Ji, Wenguang Yang, Xiao Li, Siqi Yan, Jin Yan   +7 more
wiley   +1 more source

The Effect of Aprotinin on Thrombelastography in Vitro [PDF]

Anaesthesia and Intensive Care, 1996
The effect of low dose (50 KIU/ml) and high dose (200 KIU/ml) aprotinin on standard thrombelastographic variables (r, K, α, MA) was examined in vitro using blood from forty ASA Class I patients. Both concentrations of aprotinin resulted in minor increases in r time above the normal range (P<0.05).
Neville M. Gibbs, George A. Chalkiadis
openaire   +3 more sources

Topical Use of Aprotinin in Coronary Artery Bypass Surgery

Acta Medica, 1999
Objective: The internal mammary artery (IMA) ranks among excellent, widely used conduits for surgical coronary revascularization. Its harvesting and its using may cause other surgical and technical problems and complications and increase postoperative ...
Jiří Manďák, Vladimír Lonský, Jan Dominik   +2 more
doaj   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

The effect of aprotinin (trasylol) on postoperative bleeding in cyanotic congenital heart disease

The Turkish Journal of Pediatrics, 1991
Despite the widespread clinical success in open-heart surgery, bleeding after cardiopulmonary by-pass (CPB) has been a common problem especially in cyanotic congenital heart disease.
E Hazan, I Paşaoğlu, M Demircin, A Y Bozer   +3 more
doaj  

Antifibrinolytics in liver surgery

Indian Journal of Anaesthesia, 2010
Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana, Saloni Paranjape, Jyotsna Goswami   +2 more
doaj   +1 more source

Different aprotinin applications influencing hemostatic chances in orthotopic liver transplantation [PDF]

, 1992
The effect of different aprotinin applications on hemmtatic changes and blood product requirements in orthotopic liver transplantation was investigated in a prospective, open, and randomized study.
Bechstein, W. O., Himmelreich, G., Jochum, Marianne, Muser, M., Neuhaus, P., Riess, H., Slama, K.-J.   +6 more
core  

Ectopic A-lattice seams destabilize microtubules [PDF]

, 2014
Natural microtubules typically include one A-lattice seam within an otherwise helically symmetric B-lattice tube. It is currently unclear how A-lattice seams influence microtubule dynamic instability.
A des Georges, A Desai, A Dimitrov, A Grafmuller, AA Hyman, B Vitre, D Chretien, D Chretien, D Chretien, D Chretien, D Panda, D Sept, DJ Odde, DN Drechsel, DP Dias, DR Drummond, E Nogales, EM Mandelkow, EM Mandelkow, FM Coquelle, G Brouhard, G Margolin, H Bowne-Anderson, H Sui, IM Crevel, JG Cueva, JL Hoog, JR McIntosh, JR Simon, JS Kaye, KE Busch, L Amos, L Sandblad, LG Tilney, LM Rice, M Braun, M Caplow, M Caplow, M Katsuki, M Katsuki, M Kikkawa, MK Gardner, MK Gardner, N Galjart, P Bieling, R Dallai, RA Walker, RA Walker, SP Maurer, SP Maurer, T Mitchison, T Mitchison, Y Komarova, YH Song, ZC Zhu   +54 more
core   +1 more source

Metformin Administration Protects Against Deltoid Tendon Damage Through Activation of Notch Signaling

iMeta, EarlyView.
Type 2 Diabetes Mellitus (T2DM) is a growing global health concern that is associated with severe complications including diabetic tendinopathy. In this study, we found that T2DM patients had a significantly higher prevalence of tendon surgery compared to non‐T2DM patients, which were alongside impaired ECM and cell adhesion. Notably, metformin‐treated
Can Liu, Runqi Wang, Yong Xu, Qingyi Liu, Yin Li, Xiangpeng Liu, Hui Shu, Kaige Gao, Xingye Zheng, Yingying Dong, Yijun Wang, Bin Guo, Lei Fu, Bin Zhang, Liang Zhao, Zhihao Jia, Xiaobo Sun   +16 more
wiley   +1 more source