Results 71 to 80 of about 44,465 (273)

Topical Use of Aprotinin in Coronary Artery Bypass Surgery

open access: yesActa Medica, 1999
Objective: The internal mammary artery (IMA) ranks among excellent, widely used conduits for surgical coronary revascularization. Its harvesting and its using may cause other surgical and technical problems and complications and increase postoperative ...
Jiří Manďák   +2 more
doaj   +1 more source

Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases. [PDF]

open access: yesPLoS ONE, 2015
Tryptic serine proteases of bronchial epithelium regulate ion flux, barrier integrity, and allergic inflammation. Inhibition of some of these proteases is a strategy to improve mucociliary function in cystic fibrosis and asthmatic inflammation.
Shilpa Nimishakavi   +3 more
doaj   +1 more source

Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]

open access: yes, 1994
Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O.   +6 more
core  

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro   +5 more
wiley   +1 more source

The effect of aprotinin (trasylol) on postoperative bleeding in cyanotic congenital heart disease

open access: yesThe Turkish Journal of Pediatrics, 1991
Despite the widespread clinical success in open-heart surgery, bleeding after cardiopulmonary by-pass (CPB) has been a common problem especially in cyanotic congenital heart disease.
E Hazan   +3 more
doaj  

Aprotinin during coronary-artery bypass grafting and risk of death.

open access: yesNew England Journal of Medicine, 2008
BACKGROUND Aprotinin (Trasylol) is used to mitigate bleeding during coronary-artery bypass grafting (CABG). Accumulating evidence suggests that this practice increases mortality.
S. Schneeweiss   +3 more
semanticscholar   +1 more source

Aprotinin reduces blood loss in off-pump coronary artery bypass (OPCAB) surgery [PDF]

open access: yes, 2017
Objective: Effects of aprotinin in off-pump coronary artery bypass (OPCAB) surgery have not yet been described. This study analyses hemostasiologic changes and potential benefit in OPCAB patients treated with aprotinin.
Berdat, P.A.   +5 more
core  

Self-Assembled Mucin-Containing Microcarriers via Hard Templating on CaCO3 Crystals

open access: yesMicromachines, 2018
Porous vaterite crystals of CaCO3 are extensively used for the fabrication of self-assembled polymer-based microparticles (capsules, beads, etc.) utilized for drug delivery and controlled release.
Nadezhda G. Balabushevich   +5 more
doaj   +1 more source

Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease [PDF]

open access: yes, 1992
Autoimmune chronic active liver disease (ACALD), a major indication for liver transplantation, is associated strongly with antigenic determinants HLA-B8 and DR3.
Block, GD   +6 more
core   +1 more source

Covalent Inhibition of the Peptidyl‐Prolyl Isomerase Pin1 by Sulfopin Results in a Broad Impact on the Phosphoproteome of Human Osteosarcoma U2‐OS Cells

open access: yesPROTEOMICS, Volume 25, Issue 14, July 2025.
ABSTRACT Peptidyl‐prolyl isomerase, NIMA‐interacting protein 1‐(Pin1) catalyses the cis–trans interconversion of the inflexible bond between serine or threonine residues and proline at the +1 position (pSer/pThr‐Pro). Although initially discovered as an essential regulator of cell division, Pin1 has since been identified as a regulator of many ...
Scott E. Roffey   +5 more
wiley   +1 more source

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