Results 141 to 150 of about 53,726 (303)

In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice

Advanced NanoBiomed Research, EarlyView.
Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin, Benjamin Chacon, Gulnaz Gahramanova, Inna Chorna, Zhanna Klishchova, Anastasia Konieva, Ilya Yanko, Andrii Liutyi, Milena Yalyzhko, Ivan Baginskiy, Veronika Zahorodna, Júlio Sílvio de Sousa Bueno Filho, Erfan Rezvani Ghomi, Igor Panko, Tetiana Shapochka, Oksana Sulaieva, Oleksandr Solodovnyk, Lucia Gemma Delogu, Oleksiy Gogotsi, Laura Fusco, Sergiy Kyrylenko, Yury Gogotsi, Maksym Pogorielov   +22 more
wiley   +1 more source

Aptamer-Based Folding Fluorescent Sensor for Cocaine

, 2016
We adapted in two steps a deoxyribonucleotide-based aptamer to signal the recognition of cocaine:  an instability was engineered in one stem of a three-way junction that forms the cocaine-binding pocket and the resulting short stem was end labeled with a
Paloma de Prada (2982405), Donald W. Landry (48005), Milan N. Stojanovic (2120485)   +2 more
core   +1 more source

Aptamer-targeted oligonucleotide theranostics: a smarter approach for brain delivery and the treatment of neurological diseases

, 2015
Aptamers represent the novel class of oligonucleotides holding multiple applications in the area of biomedicine. The advancements introduced with the Systematic Evolution of Ligands by EXponential enrichment (SELEX) approach further eased the scope of ...
JR Kanwar (14450679), RN Veedu (14471592), B Sriramoju (13487908), R Kanwar (14471637)   +3 more
core  

Aptamer-Based Multiparameter Analysis for Molecular Profiling of Hematological Malignancies

The subtypes of hematological malignancies (HM) with minimal molecular profile differences display an extremely heterogeneous clinical course and a discrepant response to certain treatment regimens.
Tong Wang (87696), Zhimin Wang (134383), Yuting Zhuo (10147412), Ying Peng (26452), Yue Liu (292931), Weihong Tan (9692), Hui Wu (219526), Tianhuan Peng (1531375), Liping Qiu (286577)   +8 more
core   +1 more source

Aptamer-based fluorometric determination of Salmonella Typhimurium using Fe₃O₄ magnetic separation and CdTe quantum dots - Fig 6

, 2019
(a) UV-visible absorption spectrum of 10 μL of 1 mg•mL-1 streptavidin-coated MNPs decorated with 50 μL of 10 nM aptamer. (b) Fluorescence spectra of different concentrations (from 70 μL to 10 μL) of ssDNA2@CdTe QDs of 30 μg·mL-1 ssDNA2@CdTe QDs.
Junan Ren (3847069), Gang Liang (120372), An Li (415945), Ligang Pan (762190), Yan Man (6858176), Xinxin Jin (678016), Qingju Liu (2562268)   +6 more
core   +1 more source

Aptamer-Structure Switch Coupled with Horseradish Peroxidase Labeling on a Microplate for the Sensitive Detection of Small Molecules

, 2019
Detection of small molecules with good sensitivity, high throughput, simplicity, and generality using aptamers is desired but still remains challenging. We described an aptamer-structure-switch assay coupled with horseradish peroxidase (HRP) labeling on ...
Qiang Zhao (105948), Linlin Sun (396058), Yapiao Li (4370767)   +2 more
core   +1 more source

Aptamer-Based Sandwich Assay for Measurement of Thymidine Kinase 1 in Serum of Cancerous Patients

, 2019
Thymidine kinase 1 (TK1) is traditionally a serum biomarker that is elevated in the early stages of malignancies. The diagnostic and prognostic role of TK1 for screening and monitoring human malignancies has recently been investigated.
Seyed Latif Mousavi Gargari (6619913), Mohammad Javad Rassaee (6619919), Abbas Sahebghadam Lotfi, Abbas Sahebghadam Lotfi (6619916), Mahmood Nazari, Seyed Latif Mousavi Gargari, Ramezan Ali Taheri (6619922), Mahmood Nazari (6619910), Mohammad Javad Rassaee, Ramezan Ali Taheri   +9 more
core   +1 more source

Therapeutic aptamers

Folia Pharmacologica Japonica, 2016
Tomoyuki, Abe, Shin, Miyakawa, Yoshikazu, Nakamura   +2 more
openaire   +3 more sources

Fundamentals of Aptamers and Aptamers-Based Biosensors

Antibodies or enzymes have long dominated the field of sensors and analysis, based on their most effective capture capacity for many target molecules as biorecognition. Because of this, immunoassay has developed into one of the best platforms for biosensors, including clinical diagnostics.
Cem Erkmen, Ozge Selcuk, Dilsat Ozkan-Ariksoysal, Bengi Uslu   +3 more
openaire   +3 more sources

Pseudo aptamer expands aptamer’s applications [PDF]

MOJ Bioorganic & Organic Chemistry, 2018
Hengguang Li, Grace M Chavis
openaire   +1 more source