Results 211 to 220 of about 68,358 (287)

The Graphene Oxide Memristive DNA Sensor for Taxonomic Fingerprint

Macromolecular Materials and Engineering, EarlyView.
A graphene oxide–based memristive DNA sensor enables rapid, label‐free quantification of nucleotide base composition across 37%–55% GC with strong linear calibration. Delivering results within 2–5 min, the platform combines high sensitivity with minimal sample preparation, offering a practical tool for point‐of‐care diagnostics, genetic fingerprinting,
Konstantin G. Nikolaev, Jia Hui Bong, Siyu Chen, Kostya S. Novoselov, Daria V. Andreeva   +4 more
wiley   +1 more source

Aptamer-liposome targeted nanotherapeutics for cancer therapy: Bibliometric analysis, recent developments and future perspectives. [PDF]

Mater Today Bio
Gao Z, Du S, Song J, Gao Y, Peng X, Lin X, E S, Zhao Y, Zhang S.   +8 more
europepmc   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Listeria monocytogenes detection assay via aptamer-functionalized magnetic bead enrichment coupled with RPA-CRISPR/Cas12a lateral flow strips. [PDF]

NPJ Sci Food
Wang H, Li H, Zeng D, Li Y, Yu X, Shangguan C, Liu X, Yang X, Ren H, Hu P, Lu Q, Lu S.   +11 more
europepmc   +1 more source

Accelerating Medicines Partnership® Parkinson's Disease Proteomics: A Comprehensive Resource for Advancing Parkinson's Disease Research

Movement Disorders, EarlyView.
Abstract Background Recent advances in proteomic profiling have enabled its use as a powerful approach in elucidating molecular mechanisms underlying Parkinson's disease, enabling the identification of disease‐associated protein alterations and candidate biomarkers for diagnosis, progression, and therapeutic response.
Victoria J. Dardov, Aparna Vasanthakumar, Ameya Kulkarni, Niveda Sundararaman, Rakhi Pandey, Preeti Bais, Jennifer E. Van, Maria Quinton, Barry Landin, David Vismer, Bradford Casey, Matt Bookman, Willy Nojopranoto, Erin Teeple, Can Kayatekin, Rajaraman Krishnan, Richard Hargreaves, Guhan Nagappan, S. Pablo Sardi, Sri Ramulu Pullagura, Christine Swanson‐Fischer, Accelerating Medicines Partnership Parkinson's Disease (AMP PD) Proteomics Working Group   +21 more
wiley   +1 more source

Intelligent nano‐platforms in breast cancer therapy: Current advances and future perspectives

Precision Medical Sciences, EarlyView.
The smart nano platform in breast cancer treatment is designed with advanced nanocarriers, including liposomes, hydrogels, porous nanoparticles, and aptamer‐based systems. These systems are capable of targeted drug release and response to environmental stimuli.
Tina Rahimi, Moluk Aivazi
wiley   +1 more source

Identification and diagnostic evaluation of an aptamer targeting prostate-cancer-derived small extracellular vesicles. [PDF]

Mol Ther Nucleic Acids
Ding T, Li Y, Xue L, Xiong C, Yu L, He Q, Liu J, Hao X, Zhao D.   +8 more
europepmc   +1 more source

Designer DNA‐Based Machines

SmartBot, EarlyView.
DNA machinery represents a burgeoning frontier at the intersection of robotics and nanotechnology, evolving from static nanostructure toward dynamic nanorobots. Here, the authors review the comprehensive research pipeline of designer DNA‐based nanomachines, covering the design, analysis, and fabrication. These programmable systems enable transformative
Yiquan An, Fan Wu, Yanyu Xiong, Cheng Zhang, Jian S. Dai, Lifeng Zhou   +5 more
wiley   +1 more source

Targeting intratumoral regulatory T cells by CD137 aptamer-shRNA chimeras. [PDF]

Immunother Adv
Lee KY, Mei Y, Liu H, Schwarz H.
europepmc   +1 more source

High Sensitivity Cardiac Troponin I Detection via MP‐Locked Aptamer and Multimeric DNAzyme‐Coupled Hyperbranched Hybridization Chain Reaction

Small, EarlyView.
We report a magnetic particle anchored locked aptamer platform integrated with hyperbranched HCR and DNAzyme amplification for enzyme‐free, ultrasensitive detection of cardiac troponin I. The assay achieves a 0.25 ng/L detection limit within 25 minutes and enables cross‐species MI detection, with machine learning classification reaching 90% accuracy ...
Sayantan Tripathy, Sahil Sharma, Ng Ka Wai, Siddhant Jaitpal, Anthony Dongchau, Saugat Bhattacharyya, Sonya R. Wesselowski, Ashley B. Saunders, Gerard L. Coté, Samuel B. Mabbott   +9 more
wiley   +1 more source